| Literature DB >> 23793419 |
Abstract
A likelihood based approach to obtaining non-parametric estimates of the failure time distribution is developed for the copula based model of Wang et al. (Lifetime Data Anal 18:434-445, 2012) for current status data under dependent observation. Maximization of the likelihood involves a generalized pool-adjacent violators algorithm. The estimator coincides with the standard non-parametric maximum likelihood estimate under an independence model. Confidence intervals for the estimator are constructed based on a smoothed bootstrap. It is also shown that the non-parametric failure distribution is only identifiable if the copula linking the observation and failure time distributions is fully-specified. The method is illustrated on a previously analyzed tumorigenicity dataset.Mesh:
Year: 2013 PMID: 23793419 DOI: 10.1007/s10985-013-9274-4
Source DB: PubMed Journal: Lifetime Data Anal ISSN: 1380-7870 Impact factor: 1.588