Literature DB >> 23791484

Cellular fatty acid metabolism and cancer.

Erin Currie1, Almut Schulze, Rudolf Zechner, Tobias C Walther, Robert V Farese.   

Abstract

Cancer cells often have characteristic changes in metabolism. Cellular proliferation, a common feature of all cancers, requires fatty acids for synthesis of membranes and signaling molecules. Here, we provide a view of cancer cell metabolism from a lipid perspective, and we summarize evidence that limiting fatty acid availability can control cancer cell proliferation.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID： 23791484      PMCID： PMC3742569          DOI： 10.1016/j.cmet.2013.05.017

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  80 in total

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