Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 New roles of cyclin D1.

Literature DB >> 23790801

New roles of cyclin D1.

Abstract

Cyclins encode regulatory subunits of holoenzymes that phosphorylate a variety of cellular substrates. Although the classic role of cyclins in cell cycle progression and tumorigenesis has been well characterized, new functions have been identified, including the induction of cellular migration and invasion, enhancement of angiogenesis, inhibition of mitochondrial metabolism, regulation of transcription factor signaling via a DNA-bound form, the induction of chromosomal instability, enhancement of DNA damage sensing and DNA damage repair, and feedback governing expression of the noncoding genome. This review describes the mechanisms of these new functions of cyclin D1.

Entities: Gene

Mesh：

Substances：
Cyclin D1

Year: 2013 PMID： 23790801 PMCID： PMC3702737 DOI： 10.1016/j.ajpath.2013.03.001

Source DB: PubMed Journal: Am J Pathol ISSN： 0002-9440 Impact factor: 4.307

60 in total

Review 1. The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation.

Authors: R G Pestell; C Albanese; A T Reutens; J E Segall; R J Lee; A Arnold
Journal: Endocr Rev Date: 1999-08 Impact factor: 19.871

2. BRCA1 inhibition of estrogen receptor signaling in transfected cells.

Authors: S Fan; J Wang; R Yuan; Y Ma; Q Meng; M R Erdos; R G Pestell; F Yuan; K J Auborn; I D Goldberg; E M Rosen
Journal: Science Date: 1999-05-21 Impact factor: 47.728

3. Transcriptional regulation by a DNA-associated form of cyclin D1.

Authors: Frédéric Bienvenu; Benjamin Barré; Sandrine Giraud; Sylvie Avril; Olivier Coqueret
Journal: Mol Biol Cell Date: 2005-01-19 Impact factor: 4.138

Review 4. Mechanisms leading to chromosomal instability.

Authors: Susanne M Gollin
Journal: Semin Cancer Biol Date: 2005-02 Impact factor: 15.707

5. Deregulated cyclin E induces chromosome instability.

Authors: C H Spruck; K A Won; S I Reed
Journal: Nature Date: 1999-09-16 Impact factor: 49.962

6. Rescue of cyclin D1 deficiency by knockin cyclin E.

Authors: Y Geng; W Whoriskey; M Y Park; R T Bronson; R H Medema; T Li; R A Weinberg; P Sicinski
Journal: Cell Date: 1999-06-11 Impact factor: 41.582

7. Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis.

Authors: Rinath Jeselsohn; Nelson E Brown; Lisa Arendt; Ina Klebba; Miaofen G Hu; Charlotte Kuperwasser; Philip W Hinds
Journal: Cancer Cell Date: 2010-01-19 Impact factor: 31.743

Review 8. Minireview: Cyclin D1: normal and abnormal functions.

Authors: Maofu Fu; Chenguang Wang; Zhiping Li; Toshiyuki Sakamaki; Richard G Pestell
Journal: Endocrinology Date: 2004-08-26 Impact factor: 4.736

9. Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication.

Authors: Priya Aggarwal; Matthew D Lessie; Douglas I Lin; Laura Pontano; Andrew B Gladden; Beth Nuskey; Ami Goradia; Mariusz A Wasik; Andres J P Klein-Szanto; Anil K Rustgi; Craig H Bassing; J Alan Diehl
Journal: Genes Dev Date: 2007-11-15 Impact factor: 11.361

Review 10. G1 cell-cycle control and cancer.

Authors: Joan Massagué
Journal: Nature Date: 2004-11-18 Impact factor: 49.962

95 in total

Review 1. CDK6-a review of the past and a glimpse into the future: from cell-cycle control to transcriptional regulation.

Authors: A-S Tigan; F Bellutti; K Kollmann; G Tebb; V Sexl
Journal: Oncogene Date: 2015-10-26 Impact factor: 9.867

2. Cell aging and kidney repair.

Authors: Nathan Susnik; Anette Melk; Roland Schmitt
Journal: Cell Cycle Date: 2015 Impact factor: 4.534

Review 3. The Role of CDK4/6 Inhibition in Breast Cancer.

Authors: Conleth G Murphy; Maura N Dickler
Journal: Oncologist Date: 2015-04-15

4. miR-660 promotes liver cancer cell proliferation by targeting PPP2R2A.

Authors: Yaozhen Pan; Lei Zhan; Ling Chen; Liwen Chen; Chengyi Sun
Journal: Exp Ther Med Date: 2021-04-25 Impact factor: 2.447

5. The Effect of Selective c-MET Inhibitor on Hepatocellular Carcinoma in the MET-Active, β-Catenin-Mutated Mouse Model.

Authors: Na Zhan; Adeola Adebayo Michael; Kaiyuan Wu; Gang Zeng; Aaron Bell; Junyan Tao; Satdarshan P Monga
Journal: Gene Expr Date: 2018-02-06

6. Inhibition of STAT3 reduces proliferation and invasion in salivary gland adenoid cystic carcinoma.

Authors: Lin-Lin Bu; Wei-Wei Deng; Cong-Fa Huang; Bing Liu; Wen-Feng Zhang; Zhi-Jun Sun
Journal: Am J Cancer Res Date: 2015-04-15 Impact factor: 6.166

Review 7. Cell cycle, cytoskeleton dynamics and beyond: the many functions of cyclins and CDK inhibitors.

Authors: Nawal Bendris; Bénédicte Lemmers; Jean Marie Blanchard
Journal: Cell Cycle Date: 2015 Impact factor: 4.534

8. Inhibition of heat shock protein 90 suppresses squamous carcinogenic progression in a mouse model of esophageal cancer.

Authors: Shaoxiang Wang; Zhan Du; Jie Luo; Xiao Wang; Haiying Li; Yuting Liu; Yong Zhang; Jiwei Ma; Weiwei Xiao; Yifei Wang; Xueyun Zhong
Journal: J Cancer Res Clin Oncol Date: 2015-01-07 Impact factor: 4.553

9. Everolimus induces G₁ cell cycle arrest through autophagy-mediated protein degradation of cyclin D1 in breast cancer cells.

Authors: Guang Chen; Xiao-Fei Ding; Hakim Bouamar; Kyle Pressley; Lu-Zhe Sun
Journal: Am J Physiol Cell Physiol Date: 2019-05-22 Impact factor: 4.249

10. Huaier polysaccharide induces apoptosis in hepatocellular carcinoma cells through p38 MAPK.

Authors: Haidong Bao; Peng Liu; Ke Jiang; Xianbin Zhang; Long Xie; Zhongyu Wang; Peng Gong
Journal: Oncol Lett Date: 2016-06-08 Impact factor: 2.967