Literature DB >> 23788402

Immobilization of actively thromboresistant assemblies on sterile blood-contacting surfaces.

Zheng Qu1, Venkat Krishnamurthy, Carolyn A Haller, Brent M Dorr, Ulla M Marzec, Sawan Hurst, Monica T Hinds, Stephen R Hanson, David R Liu, Elliot L Chaikof.   

Abstract

Rapid one-step modification of thrombomodulin with alkylamine derivatives such as azide, biotin, and PEG is achieved using an evolved sortase (eSrtA) mutant. The feasibility of a point-of-care scheme is demonstrated herein to site-specifically immobilize azido-thrombomodulin on sterilized commercial ePTFE vascular grafts, which exhibit superior thromboresistance compared with commercial heparin-coated grafts in a primate model of acute graft thrombosis.
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  antifouling; biocompatible materials; biomedical applications; thrombomodulin; thrombosis

Mesh：

Substances：

Year:  2013        PMID： 23788402      PMCID： PMC3955951          DOI： 10.1002/adhm.201300110

Source DB:  PubMed          Journal:  Adv Healthc Mater        ISSN： 2192-2640            Impact factor:   9.933


  63 in total

1.  Mechanistic investigation of the staudinger ligation.

Authors:  Fiona L Lin; Helen M Hoyt; Herman van Halbeek; Robert G Bergman; Carolyn R Bertozzi
Journal:  J Am Chem Soc       Date:  2005-03-02       Impact factor: 15.419

2.  Transient elastic support for vein grafts using a constricting microfibrillar polymer wrap.

Authors:  Mohammed S El-Kurdi; Yi Hong; John J Stankus; Lorenzo Soletti; William R Wagner; David A Vorp
Journal:  Biomaterials       Date:  2008-05-02       Impact factor: 12.479

3.  A general strategy for the evolution of bond-forming enzymes using yeast display.

Authors:  Irwin Chen; Brent M Dorr; David R Liu
Journal:  Proc Natl Acad Sci U S A       Date:  2011-06-22       Impact factor: 11.205

4.  Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of Staphylococcus aureus at the LPXTG motif.

Authors:  H Ton-That; G Liu; S K Mazmanian; K F Faull; O Schneewind
Journal:  Proc Natl Acad Sci U S A       Date:  1999-10-26       Impact factor: 11.205

5.  The Scandinavian Propaten(®) trial - 1-year patency of PTFE vascular prostheses with heparin-bonded luminal surfaces compared to ordinary pure PTFE vascular prostheses - a randomised clinical controlled multi-centre trial.

Authors:  J S Lindholt; B Gottschalksen; N Johannesen; D Dueholm; H Ravn; E D Christensen; B Viddal; T Flørenes; G Pedersen; M Rasmussen; M Carstensen; N Grøndal; H Fasting
Journal:  Eur J Vasc Endovasc Surg       Date:  2011-03-03       Impact factor: 7.069

6.  Covalently immobilized thrombomodulin inhibits coagulation and complement activation of artificial surfaces in vitro.

Authors:  C Sperling; K Salchert; U Streller; C Werner
Journal:  Biomaterials       Date:  2004-09       Impact factor: 12.479

7.  Clopidogrel inhibition of stent, graft, and vascular thrombogenesis with antithrombotic enhancement by aspirin in nonhuman primates.

Authors:  L A Harker; U M Marzec; A B Kelly; N R Chronos; I B Sundell; S R Hanson; J M Herbert
Journal:  Circulation       Date:  1998-12-01       Impact factor: 29.690

8.  Immobilization of human thrombomodulin onto PTFE.

Authors:  C Sperling; U König; G Hermel; C Werner; M Müller; F Simon; K Grundke; H J Jacobasch; V N Vasilets; Y Ikada
Journal:  J Mater Sci Mater Med       Date:  1997-12       Impact factor: 3.896

9.  Selective inhibition by a synthetic hirudin peptide of fibrin-dependent thrombosis in baboons.

Authors:  Y Cadroy; J M Maraganore; S R Hanson; L A Harker
Journal:  Proc Natl Acad Sci U S A       Date:  1991-02-15       Impact factor: 11.205

Review 10.  Novel thromboresistant materials.

Authors:  Sumanas W Jordan; Elliot L Chaikof
Journal:  J Vasc Surg       Date:  2007-06       Impact factor: 4.268
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  8 in total

1.  Animal models of cardiovascular disease as test beds of bioengineered vascular grafts.

Authors:  Sindhu Row; Daniel D Swartz; Stelios T Andreadis
Journal:  Drug Discov Today Dis Models       Date:  2018-06-18

Review 2.  Methods for the directed evolution of proteins.

Authors:  Michael S Packer; David R Liu
Journal:  Nat Rev Genet       Date:  2015-06-09       Impact factor: 53.242

3.  Simulated Thrombin Generation in the Presence of Surface-Bound Heparin and Circulating Tissue Factor.

Authors:  E Victoria Dydek; Elliot L Chaikof
Journal:  Ann Biomed Eng       Date:  2015-07-14       Impact factor: 3.934

4.  A rechargeable anti-thrombotic coating for blood-contacting devices.

Authors:  Hyun Ok Ham; Carolyn A Haller; Guowei Su; Erbin Dai; Madhukar S Patel; David R Liu; Jian Liu; Elliot L Chaikof
Journal:  Biomaterials       Date:  2021-07-09       Impact factor: 15.304

Review 5.  Recent advances in covalent, site-specific protein immobilization.

Authors:  Morten Meldal; Sanne Schoffelen
Journal:  F1000Res       Date:  2016-09-12

Review 6.  Broadening the scope of sortagging.

Authors:  Xiaolin Dai; Alexander Böker; Ulrich Glebe
Journal:  RSC Adv       Date:  2019-02-06       Impact factor: 4.036

7.  In vitro and ex vivo hemocompatibility of off-the-shelf modified poly(vinyl alcohol) vascular grafts.

Authors:  Marie F A Cutiongco; Deirdre E J Anderson; Monica T Hinds; Evelyn K F Yim
Journal:  Acta Biomater       Date:  2015-07-27       Impact factor: 8.947

8.  In situ regeneration of bioactive coatings enabled by an evolved Staphylococcus aureus sortase A.

Authors:  Hyun Ok Ham; Zheng Qu; Carolyn A Haller; Brent M Dorr; Erbin Dai; Wookhyun Kim; David R Liu; Elliot L Chaikof
Journal:  Nat Commun       Date:  2016-04-13       Impact factor: 14.919
  8 in total

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