Literature DB >> 23786447

Detection and characteristics of individuals with a very long duration of untreated psychosis in an early intervention for psychosis service.

Brian O'Donoghue1, John Lyne, Anthony Kinsella, Niall Turner, Eadbhard O'Callaghan, Mary Clarke.   

Abstract

AIM: Early intervention (EI) services for psychosis aim to reduce the duration of untreated psychosis (DUP) with intensive large-scale multi-focus initiatives, including public awareness campaigns. As a consequence of this approach, individuals with a very long DUP who might have otherwise remained undiagnosed may come to medical attention. The aim of this study was to investigate if an EI service detected additional cases of individuals with a first-episode psychosis (FEP) with a very long DUP and identify demographic and clinical characteristics associated with a very long DUP.
METHODS: We compared the distribution of the DUP in cases with FEP in a cohort from an EI service in a geographically defined catchment area with a historical control group. Participants were interviewed using the Structured Clinical Interview for DSM IV (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition) diagnoses and the Beiser scale to determine the DUP.
RESULTS: A total of 172 individuals were included in the EI service and 151 were included from the historical control. There was no difference in the distribution of the DUP in the EI service compared with the historical control group (χ(2)  = 3.77, degrees of freedom (d.f.) = 3, P = 0.29). In the EI service, 7.6% of cases had a DUP between 24 and 35.9 months compared to 3.3% in the historical control, and 13.4% of cases in the EI service had a DUP of greater than three years compared to 10.6% in the historical control. A very long DUP was associated with unemployment, less insight and involuntary treatment.
CONCLUSION: Further examination of the pathways to care in cases with a long DUP may clarify the contribution of help-seeking and health system delays for these individuals.
© 2013 Wiley Publishing Asia Pty Ltd.

Entities:  

Keywords:  duration of untreated psychosis; early intervention; incidence; psychosis; schizophrenia

Mesh:

Year:  2013        PMID: 23786447     DOI: 10.1111/eip.12063

Source DB:  PubMed          Journal:  Early Interv Psychiatry        ISSN: 1751-7885            Impact factor:   2.732


  4 in total

1.  Metacognitive Deficits Predict Impaired Insight in Schizophrenia Across Symptom Profiles: A Latent Class Analysis.

Authors:  Paul H Lysaker; Emily Gagen; Abigail Wright; Jenifer L Vohs; Marina Kukla; Phillip T Yanos; Ilanit Hasson-Ohayon
Journal:  Schizophr Bull       Date:  2019-01-01       Impact factor: 9.306

2.  Insight in schizophrenia spectrum disorders: relationship with behavior, mood and perceived quality of life, underlying causes and emerging treatments.

Authors:  Paul H Lysaker; Michelle L Pattison; Bethany L Leonhardt; Scott Phelps; Jenifer L Vohs
Journal:  World Psychiatry       Date:  2018-02       Impact factor: 49.548

3.  Longer Duration of Untreated Psychosis Hinders Improvement in Treatment of Chronic Schizophrenia: Community Based Early Intervention is an Evidence Based Option.

Authors:  Abdülkadir Tabo; Erkan Aydın; Hüseyin Yumrukçal; Sadık Yiğit; Uğraş Erman Uzun; Oğuz Karamustafalıoğlu
Journal:  Community Ment Health J       Date:  2017-02-10

4.  Effects of socio-demographic characteristics, premorbid functioning, and insight on duration of untreated psychosis in first-episode schizophrenia or schizophreniform disorder in Northern Malawi.

Authors:  Atipatsa C Kaminga; Wenjie Dai; Aizhong Liu; Japhet Myaba; Richard Banda; Shi W Wen
Journal:  Early Interv Psychiatry       Date:  2019-02-01       Impact factor: 2.732

  4 in total

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