Literature DB >> 23785258

The impact of chimerism in DNA-based forensic sex determination analysis.

Renjith George1, Preethy Mary Donald, Sumanth Kumbargere Nagraj, Jose Joy Idiculla, Rashid Hj Ismail.   

Abstract

Sex determination is the most important step in personal identification in forensic investigations. DNA-based sex determination analysis is comparatively more reliable than the other conventional methods of sex determination analysis. Advanced technology like real-time polymerase chain reaction (PCR) offers accurate and reproducible results and is at the level of legal acceptance. But still there are situations like chimerism where an individual possess both male and female specific factors together in their body. Sex determination analysis in such cases can give erroneous results. This paper discusses the phenomenon of chimerism and its impact on sex determination analysis in forensic investigations.

Keywords:  DNA; chimerism; forensic sciences; polymerase chain reaction; sex determination analysis

Year:  2013        PMID： 23785258      PMCID： PMC3684380     

Source DB:  PubMed          Journal:  Malays J Med Sci        ISSN： 1394-195X


  9 in total

1.  First-trimester fetal sex determination in maternal serum using real-time PCR.

Authors:  J M Costa; A Benachi; E Gautier; J M Jouannic; P Ernault; Y Dumez
Journal:  Prenat Diagn       Date:  2001-12       Impact factor: 3.050

2.  Identification of male cardiomyocytes of extracardiac origin in the hearts of women with male progeny: male fetal cell microchimerism of the heart.

Authors:  Antoni Bayes-Genis; Beatriz Bellosillo; Oscar de la Calle; Marta Salido; Santiago Roura; Francesc Solé Ristol; Carolina Soler; Monica Martinez; Blanca Espinet; Sergi Serrano; Antoni Bayes de Luna; Juan Cinca
Journal:  J Heart Lung Transplant       Date:  2005-09-28       Impact factor: 10.247

Review 3.  What do the X and Y chromosomes tell us about sex and gender in forensic case analysis?

Authors:  Nicole von Wurmb-Schwark; Hartmut Bosinski; Stefanie Ritz-Timme
Journal:  J Forensic Leg Med       Date:  2006-08-23       Impact factor: 1.614

4.  Forensic application of a rapid and quantitative DNA sex test by amplification of the X-Y homologous gene amelogenin.

Authors:  A Mannucci; K M Sullivan; P L Ivanov; P Gill
Journal:  Int J Legal Med       Date:  1994       Impact factor: 2.686

5.  Short communication: Y chromosome microchimerism in female peripheral blood.

Authors:  Lakshmi Rao; Venkata Suryanarayana; Murthy Kanakavalli; Venkata Padmalatha; Turlapati Raseswari; Nallari Pratibha; Mamata Deenadayal; Lalji Singh
Journal:  Reprod Biomed Online       Date:  2008-10       Impact factor: 3.828

Review 6.  Cell migration from baby to mother.

Authors:  Gavin S Dawe; Xiao Wei Tan; Zhi-Cheng Xiao
Journal:  Cell Adh Migr       Date:  2007-01-28       Impact factor: 3.405

7.  Persisting fetal microchimerism does not interfere with forensic Y-chromosome typing.

Authors:  M Klintschar; P Schwaiger; S Regauer; S Mannweiler; M Kleiber
Journal:  Forensic Sci Int       Date:  2004-01-28       Impact factor: 2.395

8.  Isolation of epithelial cells from acrylic removable dentures and gender identification by amplification of SRY gene using real time PCR.

Authors:  Renjith George; G Sriram; Tr Saraswathi; B Sivapathasundharam
Journal:  J Forensic Dent Sci       Date:  2010-01

9.  Practical aspects of DNA-based forensic studies in dentistry.

Authors:  J Muruganandhan; G Sivakumar
Journal:  J Forensic Dent Sci       Date:  2011-01
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.