Literature DB >> 23784690

Complications of cemented long-stem hip arthroplasty in metastatic bone disease revisited.

Shawn L Price1, M Aabid Farukhi, Kevin B Jones, Stephen K Aoki, R Lor Randall.   

Abstract

BACKGROUND: The literature suggests that a cemented long-stem femoral arthroplasty is associated with increased intraoperative and perioperative risks. Embolic events may precipitate cardiopulmonary complications and even death; by contrast, others have reported that the use of a cemented long-stem femoral arthroplasty in patients with metastatic bone disease is a safe procedure. QUESTIONS/PURPOSES: Specifically, in this study, we sought to identify (1) intraoperative complications potentially attributable to the use of cemented long-stem femoral components, and (2) early postoperative complications potentially attributable to the use of cemented long-stem femoral components in patients having an arthroplasty for metastatic bone disease.
METHODS: In this study, we performed a retrospective chart review of 42 patients (44 arthroplasties), in which the same surgical technique was used. The primary outcome measure was perioperative complications, including intraoperative cement-associated desaturation, cement-associated hypotension, sympathomimetic administration, postoperative hypotension/desaturation, and death.
RESULTS: In this series, 19% of the patients had cement-associated hypotension and sympathomimetics were administered to 48%. Two patients required prolonged intubation. One death occurred during hospitalization but there were no cardiopulmonary events.
CONCLUSIONS: This study showed that some patients experienced postoperative desaturation, prolonged intubation, and increased use of sympathomimetics, however, these events were short-lived and did not result in patient mortality. Although there are significant risks to cemented long-stem femoral arthroplasty, it can be performed with a low risk of fatal cardiopulmonary complications and remains a surgical option when treating patients with metastatic bone disease. LEVEL OF EVIDENCE: Level IV, therapeutic study. See Instructions for Authors for a complete description of levels of evidence.

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Year:  2013        PMID: 23784690      PMCID: PMC3773125          DOI: 10.1007/s11999-013-3113-5

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  16 in total

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4.  Adverse clinical events during cemented long-stem femoral arthroplasty.

Authors:  Todd Herrenbruck; E W Erickson; Timothy A Damron; John Heiner
Journal:  Clin Orthop Relat Res       Date:  2002-02       Impact factor: 4.176

5.  Economic burden of metastatic bone disease in the U.S.

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7.  Initial treatment patterns and outcome of contemporary prostate cancer patients with bone metastases at initial presentation: data from CaPSURE.

Authors:  Charles J Ryan; Eric P Elkin; Janet Cowan; Peter R Carroll
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8.  Complications of cemented long-stem hip arthroplasties in metastatic bone disease.

Authors:  R Lor Randall; Stephen K Aoki; Patrick R Olson; Steven I Bott
Journal:  Clin Orthop Relat Res       Date:  2006-02       Impact factor: 4.176

9.  The impact of new chemotherapeutic and hormone agents on survival in a population-based cohort of women with metastatic breast cancer.

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4.  Patients With Multiple Myeloma Have More Complications After Surgical Treatment of Hip Fracture.

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5.  Cemented long versus standard femoral stem in proximal femoral metastasis: a noninferiority single-blinded quasi-randomized clinical trial.

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