Literature DB >> 23782013

Stereoselective total synthesis of ieodomycins A and B and revision of the NMR spectroscopic data of ieodomycin B.

Sayantan Das1, Rajib Kumar Goswami.   

Abstract

Stereoselective total synthesis of antimicrobial marine metabolites ieodomycin A and B have been accomplished starting from commercially available 4-pentyn-1-ol featuring strategic application of the Negishi reaction, Kumada coupling, and Crimmins acetate aldol. This revises the proton NMR spectra of ieodomycin B.

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Year:  2013        PMID： 23782013     DOI： 10.1021/jo400929m

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  2 in total

Review 1.  Catalytic enantioselective synthesis of chiral organic compounds of ultra-high purity of >99% ee.

Authors:  Ei-ichi Negishi; Shiqing Xu
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2015       Impact factor: 3.493

2.  Asymmetric Total Synthesis of Ieodomycin B.

Authors:  Shuangjie Lin; Jianting Zhang; Zhibin Zhang; Tianxiang Xu; Shuangping Huang; Xiaoji Wang
Journal:  Mar Drugs       Date:  2017-01-18       Impact factor: 5.118
  2 in total

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