The volume of prostate can impact the male sexual function following photoselective vaporization of the prostate: results of a prospective analysis of 128 patients with 2-year follow-up.

OBJECTIVE: To evaluate the impact of the male sexual function following photoselective vaporization of the prostate treatment in different volume of prostates.
METHODS: One hundred and twenty-eight consecutive patients with active sexual ability who underwent prostate vaporization with the green light laser during 2009-2011 were enrolled. We divided all patients into two groups group I (<70 ml, n = 58) and group II (≥ 70 ml, n = 70) according to the volume of prostate. Two group patients were assessed by International Index of Erectile Function (IIEF-5) preoperatively and at 1, 3, 6, 12, and 24 months. We measured the IPSS, QoL, Q max, PRV PSA at the baseline, postoperation and every visit. IIF-5 questionnaires were also collected in every visit. RESULT: One hundred and twenty-eight patients were under successful operations. In the 1, 3, 6, 12 and 24 months, main parameters following operation such as Q max PRV IPSS and QoL scores had significant improved compared to baseline. However, the group II was better than group I in every visits. As the 6, 12 and 24 months of questionnaires, group II had less IIEF scores than group I. To evaluate the adverse sexual outcomes of IIEF-5 lists, the erectile dysfunction and overall unsatisfied scores of group II were much more than group I in 6-24-month visits.
CONCLUSION: The larger volume of prostate (≥ 70 ml) following PVP treatment has negative influence on sexual function in the long term (more than 6 months). The adverse sexual outcomes were significant increased after PVP in the prostate with more than 70-ml volume.

RCT Entities:   Population Interventions Outcomes