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Literature DB >> 23778852

Storable palladacycles for selective functionalization of alkyne-containing proteins.

Gang Cheng¹, Reyna K V Lim, Nan Li, Qing Lin.

Abstract

We report the facile preparation of palladacycles as storable arylpalladium(II) reagents from acetanilides via cyclopalladation. The palladacycles exhibit good stability in PBS buffer and are capable of functionalizing a metabolically encoded HPG-containing protein, thus providing a new type of biocompatible organometallic reagent for selectively functionalizing the alkyne-encoded proteins.

Entities: Chemical Disease Species

Mesh：

Substances：
Alkynes
Proteins
Palladium

Year: 2013 PMID： 23778852 PMCID： PMC3845886 DOI： 10.1039/c3cc43479f

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

17 in total

Review 1. Bioorthogonal chemistry: recent progress and future directions.

Authors: Reyna K V Lim; Qing Lin
Journal: Chem Commun (Camb) Date: 2010-01-21 Impact factor: 6.222

2. Storable arylpalladium(II) reagents for alkene labeling in aqueous media.

Authors: Rebecca L Simmons; Robert T Yu; Andrew G Myers
Journal: J Am Chem Soc Date: 2011-09-15 Impact factor: 15.419

3. Mild C-H halogenation of anilides and the isolation of an unusual palladium(I)-palladium(II) species.

Authors: Robin B Bedford; Mairi F Haddow; Charlotte J Mitchell; Ruth L Webster
Journal: Angew Chem Int Ed Engl Date: 2011-05-12 Impact factor: 15.336

4. Cellular consequences of copper complexes used to catalyze bioorthogonal click reactions.

Authors: David C Kennedy; Craig S McKay; Marc C B Legault; Dana C Danielson; Jessie A Blake; Adrian F Pegoraro; Albert Stolow; Zoltan Mester; John Paul Pezacki
Journal: J Am Chem Soc Date: 2011-10-19 Impact factor: 15.419

5. Anilide activation of adjacent C-H bonds in the palladium-catalysed Fujiwara-Moritani reaction.

Authors: Waqar Rauf; Amber L Thompson; John M Brown
Journal: Dalton Trans Date: 2010-10-11 Impact factor: 4.390

6. Synthetic applications of Pd(II)-catalyzed C-H carboxylation and mechanistic insights: expedient routes to anthranilic acids, oxazolinones, and quinazolinones.

Authors: Ramesh Giri; Jonathan K Lam; Jin-Quan Yu
Journal: J Am Chem Soc Date: 2010-01-20 Impact factor: 15.419

7. Analysis and optimization of copper-catalyzed azide-alkyne cycloaddition for bioconjugation.

Authors: Vu Hong; Stanislav I Presolski; Celia Ma; M G Finn
Journal: Angew Chem Int Ed Engl Date: 2009 Impact factor: 15.336

Review 8. The growing applications of click chemistry.

Authors: John E Moses; Adam D Moorhouse
Journal: Chem Soc Rev Date: 2007-05-03 Impact factor: 54.564

9. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

Authors: J G Herman; J R Graff; S Myöhänen; B D Nelkin; S B Baylin
Journal: Proc Natl Acad Sci U S A Date: 1996-09-03 Impact factor: 11.205

10. Bioorthogonal chemistry: fishing for selectivity in a sea of functionality.

Authors: Ellen M Sletten; Carolyn R Bertozzi
Journal: Angew Chem Int Ed Engl Date: 2009 Impact factor: 15.336

6 in total

1. Storable N-phenylcarbamate palladacycles for rapid functionalization of an alkyne-encoded protein.

Authors: Gang Cheng; Reyna K V Lim; Carlo P Ramil; Qing Lin
Journal: Chem Commun (Camb) Date: 2014-10-11 Impact factor: 6.222

2. Bioorthogonal chemistry.

Authors: Samuel L Scinto; Didier A Bilodeau; Robert Hincapie; Wankyu Lee; Sean S Nguyen; Minghao Xu; Christopher W Am Ende; M G Finn; Kathrin Lang; Qing Lin; John Paul Pezacki; Jennifer A Prescher; Marc S Robillard; Joseph M Fox
Journal: Nat Rev Methods Primers Date: 2021-04-15