| Literature DB >> 23778117 |
Hirohito Kai1, Midori Yamashita, Shigehiro Takase, Michizane Hashimoto, Hideyuki Muramatsu, Ikuko Nakamura, Koji Yoshikawa, Masami Ezaki, Kumiko Nitta, Masato Watanabe, Noriaki Inamura, Akihiko Fujie.
Abstract
The novel antifungal macrocyclic lipopeptidolactone, KB425796-A (1), was isolated from the fermentation broth of bacterial strain 530603, which was identified as a new Paenibacillus species based on morphological and physiological characteristics, and 16S rRNA sequences. KB425796-A (1) was isolated as white powder by solvent extraction, HP-20 and ODS-B column chromatography, and lyophilization, and was determined to have the molecular formula C79H115N19O18. KB425796-A (1) showed antifungal activities against Aspergillus fumigatus and the micafungin-resistant infectious fungi Trichosporon asahii, Rhizopus oryzae, Pseudallescheria boydii and Cryptococcus neoformans.Entities:
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Year: 2013 PMID： 23778117 DOI： 10.1038/ja.2013.63
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649