Literature DB >> 23775752

Discovery and customized validation of antibody targets by protein arrays and indirect ELISA.

Tara K Sigdel1, Minnie M Sarwal.   

Abstract

Because of our access to human genome data and ever improving genome sequencing and proteome analysis methods we are much better in terms of our understanding of biological processes. In addition to genomics, proteomics, and other "omics" methods, availability of more sophisticated molecular assaying methods have augmented our knowledge about immune processes towards autogeneic and allogeneic targets. High-density protein arrays are developed to analyze protein-small molecule interactions, enzyme-substrate profiling, protein-protein interaction, and immune monitoring by assessing antibodies in the serum.

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Year:  2013        PMID: 23775752      PMCID: PMC4476239          DOI: 10.1007/978-1-62703-493-7_24

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  8 in total

1.  Significance analysis of microarrays applied to the ionizing radiation response.

Authors:  V G Tusher; R Tibshirani; G Chu
Journal:  Proc Natl Acad Sci U S A       Date:  2001-04-17       Impact factor: 11.205

2.  Differential immunogenicity and clinical relevance of kidney compartment specific antigens after renal transplantation.

Authors:  Li Li; Tara Sigdel; Matthew Vitalone; Sang Ho Lee; Minnie Sarwal
Journal:  J Proteome Res       Date:  2010-11-05       Impact factor: 4.466

3.  Non-HLA antibodies to immunogenic epitopes predict the evolution of chronic renal allograft injury.

Authors:  Tara K Sigdel; Li Li; Tim Q Tran; Purvesh Khatri; Maarten Naesens; Poonam Sansanwal; Hong Dai; Szu-chuan Hsieh; Minnie M Sarwal
Journal:  J Am Soc Nephrol       Date:  2012-02-02       Impact factor: 10.121

Review 4.  Biomarker discovery using protein microarray technology platforms: antibody-antigen complex profiling.

Authors:  Dawn Mattoon; Gregory Michaud; Janie Merkel; Barry Schweitzer
Journal:  Expert Rev Proteomics       Date:  2005-12       Impact factor: 3.940

5.  Identifying compartment-specific non-HLA targets after renal transplantation by integrating transcriptome and "antibodyome" measures.

Authors:  Li Li; Persis Wadia; Rong Chen; Neeraja Kambham; Maarten Naesens; Tara K Sigdel; David B Miklos; Minnie M Sarwal; Atul J Butte
Journal:  Proc Natl Acad Sci U S A       Date:  2009-02-27       Impact factor: 11.205

6.  Compartmental localization and clinical relevance of MICA antibodies after renal transplantation.

Authors:  Li Li; Amery Chen; Abanti Chaudhuri; Neeraja Kambham; Tara Sigdel; Rong Chen; Minnie M Sarwal
Journal:  Transplantation       Date:  2010-02-15       Impact factor: 4.939

Review 7.  Profiling the proteome in renal transplantation.

Authors:  Tara K Sigdel; Sangho Lee; Minnie M Sarwal
Journal:  Proteomics Clin Appl       Date:  2011-04-26       Impact factor: 3.494

8.  Protein microarrays identify antibodies to protein kinase Czeta that are associated with a greater risk of allograft loss in pediatric renal transplant recipients.

Authors:  Scott M Sutherland; Li Li; Tara K Sigdel; Persis P Wadia; David B Miklos; Atul J Butte; Minnie M Sarwal
Journal:  Kidney Int       Date:  2009-10-07       Impact factor: 10.612

  8 in total

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