| Literature DB >> 23775739 |
Ketevan Gendzekhadze1, Laima Gaidulis, David Senitzer.
Abstract
Engraftment monitoring is critical for patients after Hematopoietic Stem Cell Transplantation (HSCT). Complete donor chimerism is the goal; therefore, early detection of rejection and relapse is crucial for guiding the patient post HSCT treatment. Quantitative PCR for chimerism testing has been reported to be highly sensitive. In this chapter we discuss the quantitative PCR (qPCR) method using 34 Indel (Insertion and Deletion) genetic markers spread over 20 different chromosomes.Entities:
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Year: 2013 PMID: 23775739 DOI: 10.1007/978-1-62703-493-7_11
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745