Literature DB >> 23773849

Balloon liver cells forming Mallory-Denk-bodies are progenitor cells.

S W French1, E Vitocruz, B A French.   

Abstract

Previous studies on both human and mice livers showed MDB formation in both drug hepatitis and hepatocellular carcinoma. Using the drug hepatitis mouse model of MDB formation, numerous markers for progenitor cells were found in the cells forming MDBs. In current study, using the drug hepatitis mouse model, we found that the MDB forming cells expressed two additional progenitor cell markers. These markers were CD49f and TLR4.
Copyright © 2013 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Integrin alpha 6 (CD49f); Mallory–Denk bodies (MDBs); Progenitor cells; Toll-like receptor 4 (TLR4); Tumor-initiating stem-like cells (TISC)

Mesh：

Substances：

Year:  2013        PMID： 23773849      PMCID： PMC3886363          DOI： 10.1016/j.yexmp.2013.06.001

Source DB:  PubMed          Journal:  Exp Mol Pathol        ISSN： 0014-4800            Impact factor:   3.362


  21 in total

1.  S-adenosylmethionine prevents the up regulation of Toll-like receptor (TLR) signaling caused by chronic ethanol feeding in rats.

Authors:  Joan Oliva; Fawzia Bardag-Gorce; Jun Li; Barbara A French; Samuel W French
Journal:  Exp Mol Pathol       Date:  2011-01-25       Impact factor: 3.362

2.  CD49f enhances multipotency and maintains stemness through the direct regulation of OCT4 and SOX2.

Authors:  Kyung-Rok Yu; Se-Ran Yang; Ji-Won Jung; Hyongbum Kim; Kinarm Ko; Dong Wook Han; Sang-Bum Park; Soon Won Choi; Soo-Kyung Kang; Hans Schöler; Kyung-Sun Kang
Journal:  Stem Cells       Date:  2012-05       Impact factor: 6.277

3.  Mallory body forming cells express the preneoplastic hepatocyte phenotype.

Authors:  Li Nan; Fawzia Bardag-Gorce; Yong Wu; Jun Li; Barbara A French; Samuel W French
Journal:  Exp Mol Pathol       Date:  2006-01-18       Impact factor: 3.362

Review 4.  The role of innate immunity in the pathogenesis of preneoplasia in drug-induced chronic hepatitis based on a mouse model.

Authors:  S W French; F Bardag-Gorce; B A French; J Li; J Oliva
Journal:  Exp Mol Pathol       Date:  2011-07-28       Impact factor: 3.362

Review 5.  Alcohol, nutrition and liver cancer: role of Toll-like receptor signaling.

Authors:  Samuel W French; Joan Oliva; Barbara A French; Jun Li; Fawzia Bardag-Gorce
Journal:  World J Gastroenterol       Date:  2010-03-21       Impact factor: 5.742

6.  Is mallory body formation a preneoplastic change? A study of 181 cases of liver bearing hepatocellular carcinoma and 82 cases of cirrhosis.

Authors:  Y Nakanuma; G Ohta
Journal:  Cancer       Date:  1985-05-15       Impact factor: 6.860

7.  The role of laminin-integrin signaling in triggering MB formation. An in vivo and in vitro study.

Authors:  Yong Wu; Li Nan; Fawzia Bardag-Gorce; Jun Li; Barbaba A French; La Toyia Wilson; Jennifer Dedes; Samuel W French
Journal:  Exp Mol Pathol       Date:  2005-08       Impact factor: 3.362

Review 8.  Cancer stem cells generated by alcohol, diabetes, and hepatitis C virus.

Authors:  Keigo Machida; Chia-Lin Chen; Jian-Chang Liu; Claudine Kashiwabara; Douglas Feldman; Samuel W French; Linda Sher; Jeong Joseph Hyeongnam; Hidekazu Tsukamoto
Journal:  J Gastroenterol Hepatol       Date:  2012-03       Impact factor: 4.029

Review 9.  Molecular events in hepatic preneoplasia: a review.

Authors:  S W French
Journal:  Exp Mol Pathol       Date:  2010-01-22       Impact factor: 3.362

10.  Mallory body formation runs parallel to gamma-glutamyl transferase induction in hepatocytes of griseofulvin-fed mice.

Authors:  J Tazawa; T Irie; S W French
Journal:  Hepatology       Date:  1983 Nov-Dec       Impact factor: 17.425
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  2 in total

1.  Taurine Attenuates Hepatic Inflammation in Chronic Alcohol-Fed Rats Through Inhibition of TLR4/MyD88 Signaling.

Authors:  Chao-Jen Lin; Chun-Ching Chiu; Yi-Chen Chen; Mu-Lin Chen; Tsai-Ching Hsu; Bor-Show Tzang
Journal:  J Med Food       Date:  2015-06-19       Impact factor: 2.786

Review 2.  Innate immunity and hepatocarcinoma: Can toll-like receptors open the door to oncogenesis?

Authors:  Jorge André Gomes Lopes; Marta Borges-Canha; Pedro Pimentel-Nunes
Journal:  World J Hepatol       Date:  2016-01-28
  2 in total

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