Krishnarajah Nirantharakumar1, Mujahid Saeed, Ian Wilson, Tom Marshall, Jamie J Coleman. 1. School of Health and Population Sciences, University of Birmingham, UK; ePrescribing Research Team, University Hospital Birmingham, Birmingham, UK; Institute of Digital Healthcare, University of Warwick, UK; Warwick Institute for the Study of Diabetes, Endocrinology and Metabolism (WISDEM), University Hospitals of Coventry and Warwickshire, Coventry, UK. Electronic address: k.nirantharan@bham.ac.uk.
Abstract
OBJECTIVE: We aimed to determine whether in-patient mortality and length of stay were greater in diabetes patients with foot disease compared to those without foot disease. METHODS: Retrospective data analysis of admissions over four years (2007-2010) to University Hospital Birmingham. Based on discharge diagnostic codes we grouped admissions into those 1) with amputation, 2) with foot disease and 3) without foot disease. Inpatient mortality and length of stay were compared between the three groups, adjusting for confounders. RESULTS: We identified 25,118 admissions with diabetes of which 1149 admissions (4.6%) had foot disease and another 195 (0.8%) had a code for lower limb amputation. When compared to those without foot disease the adjusted odds ratio for inpatient mortality was 1.31 (95% CI 1.04-1.65 P=0.02) in the foot disease group, and 1.02 (95% CI 0.56-1.85 P=0.95) in the amputation group; and the adjusted relative ratio for length of stay was 2.01 (95 CI 1.86-2.16 P<0.001) in the foot disease group and 3.08 (95% CI 2.60-3.65 P<0.001) in the amputation group. CONCLUSION: Foot disease in hospitalised patients with diabetes is associated with increased length of stay and inpatient mortality. Our study adds to evidence on excess mortality associated with diabetic foot disease and to evidence on excess mortality observed in people with diabetes admitted to hospitals.
OBJECTIVE: We aimed to determine whether in-patient mortality and length of stay were greater in diabetespatients with foot disease compared to those without foot disease. METHODS: Retrospective data analysis of admissions over four years (2007-2010) to University Hospital Birmingham. Based on discharge diagnostic codes we grouped admissions into those 1) with amputation, 2) with foot disease and 3) without foot disease. Inpatient mortality and length of stay were compared between the three groups, adjusting for confounders. RESULTS: We identified 25,118 admissions with diabetes of which 1149 admissions (4.6%) had foot disease and another 195 (0.8%) had a code for lower limb amputation. When compared to those without foot disease the adjusted odds ratio for inpatient mortality was 1.31 (95% CI 1.04-1.65 P=0.02) in the foot disease group, and 1.02 (95% CI 0.56-1.85 P=0.95) in the amputation group; and the adjusted relative ratio for length of stay was 2.01 (95 CI 1.86-2.16 P<0.001) in the foot disease group and 3.08 (95% CI 2.60-3.65 P<0.001) in the amputation group. CONCLUSION:Foot disease in hospitalised patients with diabetes is associated with increased length of stay and inpatient mortality. Our study adds to evidence on excess mortality associated with diabetic foot disease and to evidence on excess mortality observed in people with diabetes admitted to hospitals.