Literature DB >> 23773636

Rheumatic complications of inflammatory bowel disease among Arabs: a hospital-based study in Kuwait.

Khaled Al-Jarallah1, Diaa Shehab, Waleed Al-Azmi, Ahmad Al-Fadli.   

Abstract

AIM: To investigate the rheumatic complications of inflammatory bowel disease (IBD) Arab patients in relation to the clinical manifestations of IBD using the Montréal classification system in a hospital-based population in Kuwait.
METHOD: A cohort of 130 consecutive patients with IBD, either ulcerative colitis (UC) or Crohn's disease (CD) attending gastroenterology and rheumatology clinics of Kuwait University hospital from January to December 2010 were recruited. IBD diagnosis, classification, and the rheumatologic characteristics of patients were assessed and noted on a pro forma.
RESULTS: In the 130 IBD patients (mean age 32.6 ± 12.3 years), 45 (34.6%) had UC and 85 (65.4%) had CD. Forty-five (34.6%) IBD patients developed rheumatic manifestations; the difference in proportion was not significant among UC and CD patients (18 [40.0%] vs. 27 [31.7%], P = 0.215). Peripheral arthritis was seen in 41 (31.5%) IBD patients. Axial skeletal involvement presenting as a combination of spondyloarthritis with sacroiliitis was seen in 11 (8.5%) out of 130 IBD patients. Isolated sacroiliitis was seen in four (3.1%) IBD patients. Enthesopathy was seen in seven (5.4%) and dactylitis in two (1.5%) IBD patients. No statistically significant difference (P > 0.05) was detected between the frequency of the rheumatic manifestations and the IBD clinical subtypes.
CONCLUSION: This study delineates the rheumatic complications in relation to clinical manifestations (phenotypes) of IBD using the Montréal classification, in a hospital-based cohort of an Arab population. The rheumatic manifestations of IBD in our study were comparable to previously published data from other parts of the world.
© 2012 The Authors International Journal of Rheumatic Diseases © 2012 Asia Pacific League of Associations for Rheumatology and Wiley Publishing Asia Pty Ltd.

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Year:  2012        PMID: 23773636     DOI: 10.1111/j.1756-185X.2012.01811.x

Source DB:  PubMed          Journal:  Int J Rheum Dis        ISSN: 1756-1841            Impact factor:   2.454


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