| Literature DB >> 23772652 |
Pan Xie1, Chungu Xia, Hanmin Huang.
Abstract
A novel palladium-catalyzed oxidative aminocarbonylation reaction via C(sp(3))-H activation was established, which provides a convenient and general method for the construction of arylacetamides via the carbonylation reaction of alkyl aromatics and amines. By using this protocol, the marketed drug ibuprofen could be easily obtained.Entities:
Year: 2013 PMID: 23772652 DOI: 10.1021/ol401419u
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005