Ryan Ng1, Sasha Bernatsky, Elham Rahme. 1. Division of Clinical Epidemiology, McGill University Health Centre (MUHC), Montreal, Quebec, Canada.
Abstract
OBJECTIVE: To determine how duration of observation affects estimation of incidence and prevalence of systemic lupus erythematosus (SLE). METHODS: SLE incidence and prevalence estimates from data periods as brief as 3 years (2001-2003) were compared to estimates from a 15-year period (1989-2003). RESULTS: The 15-year period incidence was 5.6/100,000 (95% CI 5.0-6.1) and the prevalence was 59.1/100,000 (95% CI 57.4-60.8). When a 3-year period was used, incidence was overestimated by 238.1% and prevalence underestimated by 66.0%. CONCLUSION: SLE incidence and prevalence estimates vary considerably according to the observation period; more than 5 years of data is likely required.
OBJECTIVE: To determine how duration of observation affects estimation of incidence and prevalence of systemic lupus erythematosus (SLE). METHODS:SLE incidence and prevalence estimates from data periods as brief as 3 years (2001-2003) were compared to estimates from a 15-year period (1989-2003). RESULTS: The 15-year period incidence was 5.6/100,000 (95% CI 5.0-6.1) and the prevalence was 59.1/100,000 (95% CI 57.4-60.8). When a 3-year period was used, incidence was overestimated by 238.1% and prevalence underestimated by 66.0%. CONCLUSION:SLE incidence and prevalence estimates vary considerably according to the observation period; more than 5 years of data is likely required.
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