Literature DB >> 23771127

Osteomyelitis.

Aidan Hogan1, Volkmar G Heppert, Arnold J Suda.   

Abstract

INTRODUCTION: Osteomyelitis is a challenging diagnosis for every patient because of its protracted treatment process. Very experienced orthopaedic surgeons are needed to diagnose and treat this bacteria-related severe disorder in a right and proper way.
MATERIALS AND METHODS: Different treatment options are possible for osteomyelitis at any stage: antibiotics in the acute and chronic stage for conservative treatment or radical debridement, bone fenestration, reaming, bone troughing, the Masquelet-technique, segmental resection with callus distraction, bone grafting and even amputation as surgical therapy.
RESULTS: Depending on different stages of the disease, there are good results with every technique available-on condition that radical debridement was performed. The complication rate is remarkable so that soft tissue defects should be assessed by using flaps to close the wounds in early stages.
CONCLUSIONS: The treatment of osteomyelitis should be done in centres with expertise in the treatment of this challenging disease. Different methods should be offered by surgeons and individual treatment concepts acquired together with the patient. The treatment of complications like soft tissue defects should be provided in the same centre and performed in short time lag to the prior surgery. The cooperation of the patient and surgeons of different specialities is mandatory in these cases.

Entities:  

Mesh:

Year:  2013        PMID: 23771127     DOI: 10.1007/s00402-013-1785-7

Source DB:  PubMed          Journal:  Arch Orthop Trauma Surg        ISSN: 0936-8051            Impact factor:   3.067


  25 in total

1.  Gentamicin-Loaded Polysaccharide Membranes for Prevention and Treatment of Post-operative Wound Infections in the Skeletal System.

Authors:  Urszula Cibor; Małgorzata Krok-Borkowicz; Monika Brzychczy-Włoch; Łucja Rumian; Krzysztof Pietryga; Dominika Kulig; Wojciech Chrzanowski; Elżbieta Pamuła
Journal:  Pharm Res       Date:  2017-06-21       Impact factor: 4.200

2.  Epigenetic Modification Mediates the Increase of LAG-3+ T Cells in Chronic Osteomyelitis.

Authors:  Yicun Wang; Jun Wang; Jia Meng; Hui Jiang; Jianning Zhao; Hongbo Qian; Tao Chen
Journal:  Inflammation       Date:  2017-04       Impact factor: 4.092

3.  Prospective comparative analysis of efficacy of local debridement with or without vancomycin impregnated calcium sulphate in chronic osteomyelitis.

Authors:  Nuthan Jagadeesh; Ashish Abdul; Vishwanath M Shivalingappa; Hiranya Kumar
Journal:  J Orthop       Date:  2022-06-03

4.  The antimicrobial peptide KR-12 promotes the osteogenic differentiation of human bone marrow stem cells by stimulating BMP/SMAD signaling.

Authors:  Hui Li; Shutao Zhang; Bin'en Nie; Zhe Du; Teng Long; Bing Yue
Journal:  RSC Adv       Date:  2018-04-24       Impact factor: 4.036

5.  Antibiotic-impregnated cement spacer as definitive management for osteomyelitis.

Authors:  Xu-Sheng Qiu; Xin Zheng; Hong-fei Shi; Yan-cheng Zhu; Xia Guo; Hai-jun Mao; Guang-yue Xu; Yi-xin Chen
Journal:  BMC Musculoskelet Disord       Date:  2015-09-14       Impact factor: 2.362

Review 6.  Clinical Application of Antimicrobial Bone Graft Substitute in Osteomyelitis Treatment: A Systematic Review of Different Bone Graft Substitutes Available in Clinical Treatment of Osteomyelitis.

Authors:  T A G van Vugt; J Geurts; J J Arts
Journal:  Biomed Res Int       Date:  2016-01-21       Impact factor: 3.411

Review 7.  [Advances in clinical diagnosis and treatment of chronic osteomyelitis in adults].

Authors:  Jinglong Ma; Fuchun Yang
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2020-05-15

8.  Proteus mirabilis thoracic vertebral osteomyelitis: a case report.

Authors:  Ming-Hsiu Chiang; Mei-Hui Lee; Yung-Ching Liu; Chi-Hung Lee
Journal:  J Med Case Rep       Date:  2021-05-28

Review 9.  Inflammasomes in Alveolar Bone Loss.

Authors:  Yang Li; Junqi Ling; Qianzhou Jiang
Journal:  Front Immunol       Date:  2021-06-09       Impact factor: 7.561

Review 10.  Staphylococcus aureus vs. Osteoblast: Relationship and Consequences in Osteomyelitis.

Authors:  Jérôme Josse; Frédéric Velard; Sophie C Gangloff
Journal:  Front Cell Infect Microbiol       Date:  2015-11-26       Impact factor: 5.293

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