Literature DB >> 23771075

Correlation of dermatoscopy with the histopathological changes in the diagnosis of thin melanoma.

Loredana Ungureanu1, Simona Şenilă, Sorina Dănescu, Liliana Rogojan, Rodica Cosgarea.   

Abstract

UNLABELLED: Dermatoscopy is a non-invasive technique that enables the early diagnosis of melanoma. The purpose of the present study is to identify the dermatoscopic structures or changes that can indicate the presence of thin melanoma and their correlation with the histopathological aspect.
MATERIALS AND METHODS: Twenty-four thin melanomas diagnosed at the Department of Dermatology in Cluj-Napoca, Romania, have been assessed from the point of view of the presence of dermatoscopic structures likely to indicate malignancy. The lesions have been excised and serially sectioned to identify the histopathological correspondent of the various dermatoscopic structures.
RESULTS: The dermatoscopic analysis has indicated the following characteristics that suggest the presence of thin melanoma: irregular dots or globules, small white or grey-blue areas, some peripheral pseudopods or radial streaming, red dots at the level of the lesion or the presence of an atypical vascular pattern. As far as lesions under dermatoscopic follow-up are concerned, the following may be signs of malignant transformation: changes of the pigment network, newly appeared small white or red-blue areas or irregularly distributed dots or globules. All these structures are correlated with the histopathological changes that characterize thin melanoma.
CONCLUSIONS: Slight dermatoscopic changes are extremely important in diagnosing thin melanomas as they correlate with the histopathological aspect.

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Year:  2013        PMID: 23771075

Source DB:  PubMed          Journal:  Rom J Morphol Embryol        ISSN: 1220-0522            Impact factor:   1.033


  1 in total

Review 1.  Dermoscopy in the diagnosis of cutaneous lymphoma (Review).

Authors:  Loredana Ungureanu; Alina Vasilovici; Simona Corina Șenilă; Ioana Cosgarea; Daniel Boda
Journal:  Exp Ther Med       Date:  2022-04-07       Impact factor: 2.751

  1 in total

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