Literature DB >> 23770145

Severe immune-mediated drug-induced liver injury linked to ibandronate: a case report.

Nicolas Goossens1, Laurent Spahr, Laura Rubbia-Brandt.   

Abstract

Ibandronate is a widely used bisphosphonate with no previously well documented hepatotoxicity. We report the first case of ibandronate-related hepatotoxicity and, to our knowledge, the first case of immune-mediated drug-induced liver injury (DILI) related to bisphosphonates.
Copyright © 2013 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  AIH; ALT; AST; Bisphosphonate; CT; DILI; Drug-induced liver injury; HIV; Ibandronate; LFTs; N; RUCAM; Roussel Uclaf Causality Assessment Method; ULN; alanine aminotransferase; aspartate aminotransferase; auto-immune hepatitis; computed tomography; drug-induced liver injury; human immunodeficiency virus; liver function tests; normal; upper limit of normal

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Year:  2013        PMID： 23770145     DOI： 10.1016/j.jhep.2013.06.003

Source DB:  PubMed          Journal:  J Hepatol        ISSN： 0168-8278            Impact factor:   25.083


  2 in total

1.  Zoledronic acid-induced hepatotoxicity relieved after subsequent infusions in a Chinese woman with glucocorticoid-induced osteoporosis.

Authors:  Yan Jiang; Yong Fu; Xiao-ping Xing; Mei Li; Ou Wang; Wei-bo Xia; Xun-wu Meng
Journal:  Eur J Med Res       Date:  2015-08-22       Impact factor: 2.175

Review 2.  RUCAM in Drug and Herb Induced Liver Injury: The Update.

Authors:  Gaby Danan; Rolf Teschke
Journal:  Int J Mol Sci       Date:  2015-12-24       Impact factor: 5.923
  2 in total

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