Literature DB >> 23767946

A case of portal vein arterialization after a liver transplant.

Fabio Melandro1, Quirino Lai, Giovanni B Levi Sandri, Nicola Guglielmo, Marco Di Laudo, Vincenzo Morabito, Renzo Pretagostini, Pasquale B Berloco, Massimo Rossi.   

Abstract

Hepatic artery thrombosis represents a potentially deadly complication after a liver transplant. Portal vein arterialization recently has been proposed as a bridge approach in patients with hepatic artery thrombosis needing a retransplant. We report the case of a 53-year-old man treated with a liver transplant for a cryptogenetic cirrhosis. One month after a liver transplant, a hepatic artery thrombosis was documented, and a portal vein arterialization as bridge therapy for another liver transplant was performed. After surgery, improvement in the patient's liver functioning was seen. No signs of portal hypertension or hepatic abscesses were documented. Unfortunately, 8 months after the liver transplant, the patient experienced a severe urinary infection caused by a multidrug-resistant Klebsiella and died. An increase in the oxygen supply to the liver parenchyma after portal vein arterializations represents rationale use for managing hepatic artery thromboses. Several cases of treating post liver transplant hepatic artery thromboses have been reported in the literature. Portal vein arterializations can be used as bridge therapy in well-selected situations of post-liver transplant hepatic artery thromboses. Strict surveillance should be used to prevent the onset of complications that can exclude a patient from a transplant. The correct timing for retransplant is not fully known, but we think the shorter the time to retransplant, the better is the patient survival.

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Year:  2013        PMID: 23767946     DOI: 10.6002/ect.2012.0172

Source DB:  PubMed          Journal:  Exp Clin Transplant        ISSN: 1304-0855            Impact factor:   0.945


  4 in total

Review 1.  From portal to splanchnic venous thrombosis: What surgeons should bear in mind.

Authors:  Quirino Lai; Gabriele Spoletini; Rafael S Pinheiro; Fabio Melandro; Nicola Guglielmo; Jan Lerut
Journal:  World J Hepatol       Date:  2014-08-27

2.  A new rat model of auxiliary partial heterotopic liver transplantation with liver dual arterial blood supply.

Authors:  Jianliang Qiao; Chunlei Han; Junjing Zhang; Zhiyong Wang; Xingkai Meng
Journal:  Exp Ther Med       Date:  2014-12-05       Impact factor: 2.447

3.  Liver dual arterial blood supply maintains liver regeneration: Analysis of signaling pathways in rats.

Authors:  Jian-Liang Qiao; Juan Sun; Jun Li; Jun-Jing Zhang; Xing-Kai Meng
Journal:  Mol Med Rep       Date:  2017-11-03       Impact factor: 2.952

4.  Price to pay; Portal vein arterialization for hepatic artery thrombosis after living donor liver transplantation; A case report.

Authors:  Worakitti Lapisatepun; Anon Chotirosniramit; Trichak Sandhu; Kanya Udomsin; Wasana Ko-Iam; Phuriphong Chanthima; Warangkana Lapisatepun; Settapong Boonsri; Suraphong Lorsomradee; Quanhathai Kaewpoowat; Sunhawit Junrungsee
Journal:  Int J Surg Case Rep       Date:  2018-05-02
  4 in total

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