Literature DB >> 23765707

Maternal obesity and risk of postcesarean wound complications.

Shayna N Conner1, Juliana C Verticchio1, Methodius G Tuuli1, Anthony O Odibo1, George A Macones1, Alison G Cahill1.   

Abstract

OBJECTIVE: To estimate the effect of increasing severity of obesity on postcesarean wound complications and surgical characteristics. STUDY
DESIGN: We performed a retrospective cohort study of consecutive cesarean deliveries at a tertiary care facility from 2004 to 2008. Four comparison groups were defined by body mass index (BMI; kg/cm2): < 30 (n = 728), 30 to 39.9 (n = 1,087), 40 to 49.9 (n = 428), or ≥ 50 (n = 201). The primary outcome was wound complication, defined as wound disruption or infection within 6 weeks postoperatively. Surgical characteristics were compared between groups including administration of preoperative antibiotics, type of skin incision, estimated blood loss (EBL), operative time, and type of skin closure.
RESULTS: Of the 2,444 women with complete follow-up data, 266 (10.9%) developed a wound complication. Compared with nonobese women (6.6%), increasing BMI was associated with an increased risk of wound complications: BMI 30.0 to 39.9, 9.2%, adjusted odds ratio (aOR) 1.4 (95% confidence interval [CI] 0.99 to 2.0); BMI 40.0 to 49.9, 16.8%, aOR 2.6 (95% CI 1.7 to 3.8); BMI ≥ 50, 22.9%, aOR 3.0 (95% CI 1.9 to 4.9). Increasing BMI was also associated with increased rates of midline vertical incision, longer operative time, higher EBL, and lower rates of subcuticular skin closure.
CONCLUSION: A dose-response relationship exists between increasing BMI and risk of postcesarean wound complications. Increasing obesity also significantly influences operative outcomes. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

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Year:  2013        PMID: 23765707      PMCID: PMC3796045          DOI: 10.1055/s-0033-1348402

Source DB:  PubMed          Journal:  Am J Perinatol        ISSN: 0735-1631            Impact factor:   1.862


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Authors:  T S Usha Kiran; S Hemmadi; J Bethel; J Evans
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5.  Risk factors for postcesarean surgical site infection.

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6.  Wound complications in obese women after cesarean: a comparison of staples versus subcuticular suture.

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8.  Effect of Prophylactic Negative Pressure Wound Therapy vs Standard Wound Dressing on Surgical-Site Infection in Obese Women After Cesarean Delivery: A Randomized Clinical Trial.

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9.  The association between surgical site infections and gestational weight gain in obese women.

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10.  Functional and genomic adaptations of blood monocytes to pregravid obesity during pregnancy.

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