Literature DB >> 23765500

Properties of native brain α-synuclein.

Jacqueline Burré1, Sandro Vivona, Jiajie Diao, Manu Sharma, Axel T Brunger, Thomas C Südhof.   

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Year:  2013        PMID： 23765500      PMCID： PMC4255827          DOI： 10.1038/nature12125

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  14 in total

1.  Stabilization of partially folded conformation during alpha-synuclein oligomerization in both purified and cytosolic preparations.

Authors:  V N Uversky; H J Lee; J Li; A L Fink; S J Lee
Journal:  J Biol Chem       Date:  2001-11-23       Impact factor: 5.157

Review 2.  Recent advances in the genetics of Parkinson's disease.

Authors:  Ian Martin; Valina L Dawson; Ted M Dawson
Journal:  Annu Rev Genomics Hum Genet       Date:  2011       Impact factor: 8.929

Review 3.  Analysis of post-translational modifications by LC-MS/MS.

Authors:  Hannah Johnson; Claire E Eyers
Journal:  Methods Mol Biol       Date:  2010

4.  α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.

Authors:  Bruno Fauvet; Martial K Mbefo; Mohamed-Bilal Fares; Carole Desobry; Sarah Michael; Mustafa T Ardah; Elpida Tsika; Philippe Coune; Michel Prudent; Niels Lion; David Eliezer; Darren J Moore; Bernard Schneider; Patrick Aebischer; Omar M El-Agnaf; Eliezer Masliah; Hilal A Lashuel
Journal:  J Biol Chem       Date:  2012-02-07       Impact factor: 5.157

5.  NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded.

Authors:  P H Weinreb; W Zhen; A W Poon; K A Conway; P T Lansbury
Journal:  Biochemistry       Date:  1996-10-29       Impact factor: 3.162

6.  Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes.

Authors:  W S Davidson; A Jonas; D F Clayton; J M George
Journal:  J Biol Chem       Date:  1998-04-17       Impact factor: 5.157

7.  A broken alpha -helix in folded alpha -Synuclein.

Authors:  Sreeganga Chandra; Xiaocheng Chen; Josep Rizo; Reinhard Jahn; Thomas C Südhof
Journal:  J Biol Chem       Date:  2003-02-13       Impact factor: 5.157

8.  Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro.

Authors:  Jacqueline Burré; Manu Sharma; Theodoros Tsetsenis; Vladimir Buchman; Mark R Etherton; Thomas C Südhof
Journal:  Science       Date:  2010-08-26       Impact factor: 47.728

9.  α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation.

Authors:  Tim Bartels; Joanna G Choi; Dennis J Selkoe
Journal:  Nature       Date:  2011-08-14       Impact factor: 49.962

10.  Impact of N-terminal acetylation of α-synuclein on its random coil and lipid binding properties.

Authors:  Alexander S Maltsev; Jinfa Ying; Ad Bax
Journal:  Biochemistry       Date:  2012-06-14       Impact factor: 3.162
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  121 in total

Review 1.  Dynamic structural flexibility of α-synuclein.

Authors:  Danielle E Mor; Scott E Ugras; Malcolm J Daniels; Harry Ischiropoulos
Journal:  Neurobiol Dis       Date:  2015-12-31       Impact factor: 5.996

2.  Definition of a molecular pathway mediating α-synuclein neurotoxicity.

Authors:  Jacqueline Burré; Manu Sharma; Thomas C Südhof
Journal:  J Neurosci       Date:  2015-04-01       Impact factor: 6.167

Review 3.  The role of lipids in α-synuclein misfolding and neurotoxicity.

Authors:  Cathryn L Ugalde; Victoria A Lawson; David I Finkelstein; Andrew F Hill
Journal:  J Biol Chem       Date:  2019-05-07       Impact factor: 5.157

4.  N-terminal acetylation stabilizes N-terminal helicity in lipid- and micelle-bound α-synuclein and increases its affinity for physiological membranes.

Authors:  Igor Dikiy; David Eliezer
Journal:  J Biol Chem       Date:  2013-12-12       Impact factor: 5.157

5.  Direct Detection of α-Synuclein Dimerization Dynamics: Single-Molecule Fluorescence Analysis.

Authors:  Zhengjian Lv; Alexey V Krasnoslobodtsev; Yuliang Zhang; Daniel Ysselstein; Jean-Christophe Rochet; Scott C Blanchard; Yuri L Lyubchenko
Journal:  Biophys J       Date:  2015-04-21       Impact factor: 4.033

6.  Cysteine cathepsins are essential in lysosomal degradation of α-synuclein.

Authors:  Ryan P McGlinchey; Jennifer C Lee
Journal:  Proc Natl Acad Sci U S A       Date:  2015-07-13       Impact factor: 11.205

Review 7.  Solution NMR of SNAREs, complexin and α-synuclein in association with membrane-mimetics.

Authors:  Binyong Liang; Lukas K Tamm
Journal:  Prog Nucl Magn Reson Spectrosc       Date:  2018-02-08       Impact factor: 9.795

Review 8.  Interplay between α-synuclein amyloid formation and membrane structure.

Authors:  Emma I O'Leary; Jennifer C Lee
Journal:  Biochim Biophys Acta Proteins Proteom       Date:  2018-10-02       Impact factor: 3.036

9.  Late stages of hematopoiesis and B cell lymphopoiesis are regulated by α-synuclein, a key player in Parkinson's disease.

Authors:  Wenbin Xiao; Afshin Shameli; Clifford V Harding; Howard J Meyerson; Robert W Maitta
Journal:  Immunobiology       Date:  2014-07-22       Impact factor: 3.144

10.  KTKEGV repeat motifs are key mediators of normal α-synuclein tetramerization: Their mutation causes excess monomers and neurotoxicity.

Authors:  Ulf Dettmer; Andrew J Newman; Victoria E von Saucken; Tim Bartels; Dennis Selkoe
Journal:  Proc Natl Acad Sci U S A       Date:  2015-07-07       Impact factor: 11.205
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