Literature DB >> 23761226

Repair of the (6-4) photoproduct by DNA photolyase requires two photons.

Junpei Yamamoto1, Ryan Martin, Shigenori Iwai, Pascal Plaza, Klaus Brettel.   

Abstract

It takes two (photons) to tango: Single-turnover flash experiments showed that the flavoenzyme (6-4) photolyase uses a successive two-photon mechanism to repair the UV-induced T(6-4)T lesion in DNA (see picture). The intermediate (X) formed by the first photoreaction is likely to be the oxetane-bridged dimer T(ox)T. The enzyme could stabilize the normally short-lived T(ox)T, allowing repair to be completed by the second photoreaction.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  (6-4) photoproducts; DNA damage; DNA repair; enzyme catalysis; photolyases

Mesh：

Substances：

Year:  2013        PMID： 23761226     DOI： 10.1002/anie.201301567

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  15 in total

Review 1.  Photolyase: Dynamics and electron-transfer mechanisms of DNA repair.

Authors:  Meng Zhang; Lijuan Wang; Dongping Zhong
Journal:  Arch Biochem Biophys       Date:  2017-08-09       Impact factor: 4.013

Review 2.  Prevention of Photocarcinogenesis by Agonists of 5-HT1A and Antagonists of 5-HT2A Receptors.

Authors:  Ana Catarina Menezes; Sara Raposo; Sandra Simões; Helena Ribeiro; Helena Oliveira; Andreia Ascenso
Journal:  Mol Neurobiol       Date:  2015-01-15       Impact factor: 5.590

Review 3.  Photolyase: Dynamics and Mechanisms of Repair of Sun-Induced DNA Damage.

Authors:  Meng Zhang; Lijuan Wang; Dongping Zhong
Journal:  Photochem Photobiol       Date:  2017-01-25       Impact factor: 3.421

4.  Identification and characterization of a prokaryotic 6-4 photolyase from Synechococcus elongatus with a deazariboflavin antenna chromophore.

Authors:  Simeng Chen; Chenxi Liu; Chenchen Zhou; Zhihui Wei; Yuting Li; Lei Xiong; Liang Yan; Jun Lv; Liang Shen; Lei Xu
Journal:  Nucleic Acids Res       Date:  2022-06-10       Impact factor: 19.160

5.  Pushing the limits of flash photolysis to unravel the secrets of biological electron and proton transfer.

Authors:  Paul Mathis; Evelyne Sage; Martin Byrdin
Journal:  Photochem Photobiol Sci       Date:  2022-01-26       Impact factor: 4.328

6.  Coulomb and CH-π interactions in (6-4) photolyase-DNA complex dominate DNA binding and repair abilities.

Authors:  Yuma Terai; Ryuma Sato; Takahiro Yumiba; Ryuhei Harada; Kohei Shimizu; Tatsuya Toga; Tomoko Ishikawa-Fujiwara; Takeshi Todo; Shigenori Iwai; Yasuteru Shigeta; Junpei Yamamoto
Journal:  Nucleic Acids Res       Date:  2018-07-27       Impact factor: 16.971

7.  Characterization of the Intermediate in and Identification of the Repair Mechanism of (6-4) Photolesions by Photolyases.

Authors:  Shirin Faraji; Dongping Zhong; Andreas Dreuw
Journal:  Angew Chem Int Ed Engl       Date:  2016-03-21       Impact factor: 15.336

Review 8.  Structural biology of DNA (6-4) photoproducts formed by ultraviolet radiation and interactions with their binding proteins.

Authors:  Hideshi Yokoyama; Ryuta Mizutani
Journal:  Int J Mol Sci       Date:  2014-11-06       Impact factor: 5.923

9.  White collar 1-induced photolyase expression contributes to UV-tolerance of Ustilago maydis.

Authors:  Annika Brych; Judita Mascarenhas; Elaine Jaeger; Elzbieta Charkiewicz; Richard Pokorny; Michael Bölker; Gunther Doehlemann; Alfred Batschauer
Journal:  Microbiologyopen       Date:  2015-12-20       Impact factor: 3.139

10.  Theoretical Study on the Photo-Oxidation and Photoreduction of an Azetidine Derivative as a Model of DNA Repair.

Authors:  Miriam Navarrete-Miguel; Antonio Francés-Monerris; Miguel A Miranda; Virginie Lhiaubet-Vallet; Daniel Roca-Sanjuán
Journal:  Molecules       Date:  2021-05-14       Impact factor: 4.411
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