Literature DB >> 23761109

Efficacy of lacosamide on seizures and myoclonus in a patient with epilepsia partialis continua.

Maddalena Spalletti1, Angela Comanducci, Alessandro Vagaggini, Luca Bucciardini, Antonello Grippo, Aldo Amantini.   

Abstract

A 39-year-old male with epilepsia partialis continua, refractory to first- and second-line antiepileptic drugs, is described. Lacosamide produced a progressive antiepileptic effect on Jacksonian motor seizures and subsequently on positive myoclonus, which developed into negative myoclonus before complete resolution. Our report confirms the efficacy of lacosamide on focal motor refractory status epilepticus and documents a unique effect of lacosamide on seizure semiology.

Entities:  

Keywords:  epilepsia partialis continua; lacosamide; myoclonus; negative myoclonus; refractory status epilepticus

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Year:  2013        PMID： 23761109     DOI： 10.1684/epd.2013.0565

Source DB:  PubMed          Journal:  Epileptic Disord        ISSN： 1294-9361            Impact factor:   1.819


  2 in total

Review 1.  The efficacy of lacosamide as monotherapy and adjunctive therapy in focal epilepsy and its use in status epilepticus: clinical trial evidence and experience.

Authors:  Sebastian Bauer; Laurent M Willems; Esther Paule; Christine Petschow; Johann Philipp Zöllner; Felix Rosenow; Adam Strzelczyk
Journal:  Ther Adv Neurol Disord       Date:  2016-11-29       Impact factor: 6.570

2.  Efficacy of perampanel in a patient with epilepsia partialis continua.

Authors:  H Argente-Escrig; A Gómez-Ibáñez; V Villanueva
Journal:  Epilepsy Behav Case Rep       Date:  2017-09-27
  2 in total

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