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Literature DB >> 23760245

NS1' colocalizes with NS1 and can substitute for NS1 in West Nile virus replication.

Lucy B Young¹, Ezequiel Balmori Melian, Alexander A Khromykh.

Abstract

NS1' is a C-terminally extended form of the NS1 protein produced only by encephalitic flaviviruses from the Japanese encephalitis virus serogroup. Here we show that West Nile virus (WNV) NS1' and NS1 localize to the same cellular compartments when expressed from plasmid DNAs and also colocalize to viral RNA replication sites in infected cells. Using complementation analysis with NS1-deleted WNV cDNA, we demonstrated that NS1' is able to substitute for the crucial function of NS1 in virus replication.

Entities: Disease Species

Mesh：

Substances：

Year: 2013 PMID： 23760245 PMCID： PMC3754067 DOI： 10.1128/JVI.01101-13

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

30 in total

1. cis- and trans-acting elements in flavivirus RNA replication.

Authors: A A Khromykh; P L Sedlak; E G Westaway
Journal: J Virol Date: 2000-04 Impact factor: 5.103

Review 2. Kunjin virus: an Australian variant of West Nile?

Authors: R A Hall; J H Scherret; J S Mackenzie
Journal: Ann N Y Acad Sci Date: 2001-12 Impact factor: 5.691

Review 3. Molecular biology of flaviviruses.

Authors: Brett D Lindenbach; Charles M Rice
Journal: Adv Virus Res Date: 2003 Impact factor: 9.937

4. Complete genome sequences and phylogenetic analysis of West Nile virus strains isolated from the United States, Europe, and the Middle East.

Authors: Robert S Lanciotti; Gregory D Ebel; Vincent Deubel; Amy J Kerst; Severine Murri; Richard Meyer; Michael Bowen; Nancy McKinney; William E Morrill; Mary B Crabtree; Laura D Kramer; John T Roehrig
Journal: Virology Date: 2002-06-20 Impact factor: 3.616

Review 5. Replication and gene function in Kunjin virus.

Authors: E G Westaway; J M Mackenzie; A A Khromykh
Journal: Curr Top Microbiol Immunol Date: 2002 Impact factor: 4.291

Review 6. The ecology and epidemiology of Kunjin virus.

Authors: R A Hall; A K Broom; D W Smith; J S Mackenzie
Journal: Curr Top Microbiol Immunol Date: 2002 Impact factor: 4.291

7. Nucleotide and complete amino acid sequences of Kunjin virus: definitive gene order and characteristics of the virus-specified proteins.

Authors: G Coia; M D Parker; G Speight; M E Byrne; E G Westaway
Journal: J Gen Virol Date: 1988-01 Impact factor: 3.891

8. Virulence determinants between New York 99 and Kunjin strains of West Nile virus.

Authors: Michelle Audsley; Judith Edmonds; Wenjun Liu; Vlad Mokhonov; Ekaterina Mokhonova; Ezequeil Balmori Melian; Natalie Prow; Roy A Hall; Alexander A Khromykh
Journal: Virology Date: 2011-04-07 Impact factor: 3.616

Review 9. Kunjin RNA replication and applications of Kunjin replicons.

Authors: Edwin G Westaway; Jason M Mackenzie; Alexander A Khromykh
Journal: Adv Virus Res Date: 2003 Impact factor: 9.937

10. Expression of Japanese encephalitis virus antigens in Escherichia coli.

Authors: P W Mason; P C McAda; J M Dalrymple; M J Fournier; T L Mason
Journal: Virology Date: 1987-06 Impact factor: 3.616

12 in total

1. Ablation of Programmed -1 Ribosomal Frameshifting in Venezuelan Equine Encephalitis Virus Results in Attenuated Neuropathogenicity.

Authors: Joseph A Kendra; Cynthia de la Fuente; Ashwini Brahms; Caitlin Woodson; Todd M Bell; Bin Chen; Yousuf A Khan; Jonathan L Jacobs; Kylene Kehn-Hall; Jonathan D Dinman
Journal: J Virol Date: 2017-01-18 Impact factor: 5.103

2. Dengue Virus NS1 Protein Modulates Cellular Energy Metabolism by Increasing Glyceraldehyde-3-Phosphate Dehydrogenase Activity.

Authors: Diego Allonso; Iamara S Andrade; Jonas N Conde; Diego R Coelho; Daniele C P Rocha; Manuela L da Silva; Gustavo T Ventura; Emiliana M Silva; Ronaldo Mohana-Borges
Journal: J Virol Date: 2015-09-16 Impact factor: 5.103

3. Establishment of an Algorithm Using prM/E- and NS1-Specific IgM Antibody-Capture Enzyme-Linked Immunosorbent Assays in Diagnosis of Japanese Encephalitis Virus and West Nile Virus Infections in Humans.

Authors: Jedhan U Galula; Gwong-Jen J Chang; Shih-Te Chuang; Day-Yu Chao
Journal: J Clin Microbiol Date: 2015-12-09 Impact factor: 5.948

4. Programmed ribosomal frameshift alters expression of west nile virus genes and facilitates virus replication in birds and mosquitoes.

Authors: Ezequiel Balmori Melian; Sonja Hall-Mendelin; Fangyao Du; Nick Owens; Angela M Bosco-Lauth; Tomoko Nagasaki; Stephen Rudd; Aaron C Brault; Richard A Bowen; Roy A Hall; Andrew F van den Hurk; Alexander A Khromykh
Journal: PLoS Pathog Date: 2014-11-06 Impact factor: 6.823

9. Dengue Virus Non-structural Protein 1 Modulates Infectious Particle Production via Interaction with the Structural Proteins.

Authors: Pietro Scaturro; Mirko Cortese; Laurent Chatel-Chaix; Wolfgang Fischl; Ralf Bartenschlager
Journal: PLoS Pathog Date: 2015-11-12 Impact factor: 6.823

Review 10. Replication cycle and molecular biology of the West Nile virus.

Authors: Margo A Brinton
Journal: Viruses Date: 2013-12-27 Impact factor: 5.048