Literature DB >> 23759411

Common standards of basal insulin titration in type 2 diabetes.

Sabine Arnolds1, Tim Heise, Frank Flacke, Jochen Sieber.   

Abstract

Type 2 diabetes mellitus has become a worldwide major health problem, and the number of people affected is steadily increasing. Thus, not all patients suffering from the disease can be treated by specialized diabetes centers or outpatient clinics, but by primary care physicians. The latter, however, might have time constraints and have to deal with many kinds of diseases or with multimorbid patients, so their focus is not so much on lowering high blood glucose values. Thus, the physicians, as well as the patients themselves, are often reluctant to initiate and adjust insulin therapy, although basal insulin therapy is considered the appropriate strategy after oral antidiabetic drug failure, according to the latest international guidelines. A substantial number of clinical studies have shown that insulin initiation and optimization can be managed successfully by using titration algorithms-even in cases where patients themselves are the drivers of insulin titration. Nevertheless, tools and strategies are needed to facilitate this process in the daily life of both primary health care professionals and patients with diabetes.
© 2013 Diabetes Technology Society.

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Year:  2013        PMID: 23759411      PMCID: PMC3869146          DOI: 10.1177/193229681300700323

Source DB:  PubMed          Journal:  J Diabetes Sci Technol        ISSN: 1932-2968


  69 in total

1.  Insulin glargine benefits patients with type 2 diabetes inadequately controlled on oral antidiabetic treatment: an observational study of everyday practice in 12,216 patients.

Authors:  S A Schreiber; T Haak
Journal:  Diabetes Obes Metab       Date:  2007-01       Impact factor: 6.577

Review 2.  Addressing barriers to initiation of insulin in patients with type 2 diabetes.

Authors:  Mark Peyrot; Richard R Rubin; Kamlesh Khunti
Journal:  Prim Care Diabetes       Date:  2010-04       Impact factor: 2.459

3.  Initiating insulin therapy in type 2 Diabetes: a comparison of biphasic and basal insulin analogs.

Authors:  Philip Raskin; Elsie Allen; Priscilla Hollander; Andrew Lewin; Robert A Gabbay; Peter Hu; Bruce Bode; Alan Garber
Journal:  Diabetes Care       Date:  2005-02       Impact factor: 19.112

4.  Implementation of a tight glycaemic control protocol using a web-based insulin dose calculator.

Authors:  A N Thomas; A E Marchant; M C Ogden; S Collin
Journal:  Anaesthesia       Date:  2005-11       Impact factor: 6.955

5.  The patient-perceived difficulty in diabetes treatment (PDDT) scale identifies barriers to care.

Authors:  Orly Tamir; Julio Wainstein; Ifat Abadi-Korek; Einav Horowitz; Joshua Shemer
Journal:  Diabetes Metab Res Rev       Date:  2012-03       Impact factor: 4.876

6.  Rationale, design, and baseline data of the insulin glargine (Lantus) versus insulin detemir (Levemir) Treat-To-Target (L2T3) study: A multinational, randomized noninferiority trial of basal insulin initiation in type 2 diabetes.

Authors:  Sanne G H A Swinnen; Frank J Snoek; Marie-Paule Dain; J Hans DeVries; Joost B L Hoekstra; Frits Holleman
Journal:  Diabetes Technol Ther       Date:  2009-11       Impact factor: 6.118

7.  Three-year efficacy of complex insulin regimens in type 2 diabetes.

Authors:  Rury R Holman; Andrew J Farmer; Melanie J Davies; Jonathan C Levy; Julie L Darbyshire; Joanne F Keenan; Sanjoy K Paul
Journal:  N Engl J Med       Date:  2009-10-22       Impact factor: 91.245

8.  Comparison of insulin analogue regimens in people with type 2 diabetes mellitus in the PREFER Study: a randomized controlled trial.

Authors:  A Liebl; R Prager; K Binz; M Kaiser; R Bergenstal; B Gallwitz
Journal:  Diabetes Obes Metab       Date:  2008-07-17       Impact factor: 6.577

9.  First insulinization with basal insulin in patients with Type 2 diabetes in a real-world setting in Asia.

Authors:  Shih-Tzer Tsai; Faruque Pathan; Linong Ji; Vincent Tok Fai Yeung; Manoj Chadha; Ketut Suastika; Hyun Shik Son; Kevin Eng Kiat Tan; Yupin Benjasuratwong; Thy Khue Nguyen; Farrukh Iqbal
Journal:  J Diabetes       Date:  2011-09       Impact factor: 4.006

Review 10.  Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).

Authors:  Silvio E Inzucchi; Richard M Bergenstal; John B Buse; Michaela Diamant; Ele Ferrannini; Michael Nauck; Anne L Peters; Apostolos Tsapas; Richard Wender; David R Matthews
Journal:  Diabetes Care       Date:  2012-04-19       Impact factor: 19.112

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  17 in total

1.  Real-World Data Collection Regarding Titration Algorithms for Insulin Glargine in Patients With Type 2 Diabetes Mellitus.

Authors:  Andreas Pfützner; Bernd Stratmann; Klaus Funke; Harald Pohlmeier; Ludger Rose; Jochen Sieber; Frank Flacke; Diethelm Tschoepe
Journal:  J Diabetes Sci Technol       Date:  2016-08-22

Review 2.  Overbasalization: Addressing Hesitancy in Treatment Intensification Beyond Basal Insulin.

Authors:  Kevin Cowart
Journal:  Clin Diabetes       Date:  2020-07

3.  A Simplified Approach Using Rate of Change Arrows to Adjust Insulin With Real-Time Continuous Glucose Monitoring.

Authors:  David C Klonoff; David Kerr
Journal:  J Diabetes Sci Technol       Date:  2017-09-08

4.  In Silico Examination of Initiation of Long-Acting Insulin Analogs Toujeo Compared to Lantus Under 3 Dosing Titration Rules in Virtual Type 2 Diabetes Subjects.

Authors:  Jochen Sieber; Mark Weinheimer; Gail Kongable; Susan Riddle; Yung-Yeh Chang; Frank Flacke
Journal:  J Diabetes Sci Technol       Date:  2019-07-09

5.  Feasibility of a New Approach to Initiate Insulin in Type 2 Diabetes.

Authors:  Tinna B Aradóttir; Henrik Bengtsson; Morten L Jensen; Niels K Poulsen; Dimitri Boiroux; Lea L Jensen; Signe Schmidt; Kirsten Nørgaard
Journal:  J Diabetes Sci Technol       Date:  2020-01-15

6.  Starting insulin in type 2 diabetes: real-world outcomes after the first 12 months of insulin therapy in a new zealand cohort.

Authors:  Shekhar Sehgal; Manish Khanolkar
Journal:  Diabetes Ther       Date:  2015-02-14       Impact factor: 2.945

7.  Modulation of insulin dose titration using a hypoglycaemia-sensitive algorithm: insulin glargine versus neutral protamine Hagedorn insulin in insulin-naïve people with type 2 diabetes.

Authors:  P D Home; G B Bolli; C Mathieu; C Deerochanawong; W Landgraf; C Candelas; V Pilorget; M-P Dain; M C Riddle
Journal:  Diabetes Obes Metab       Date:  2014-07-12       Impact factor: 6.577

8.  Initiating insulin: How to help people with type 2 diabetes start and continue insulin successfully.

Authors:  William H Polonsky; Joyce Arsenault; Lawrence Fisher; Pamela Kushner; Eden M Miller; Teresa L Pearson; Mariusz Tracz; Stewart Harris; Norbert Hermanns; Bernd-M Scholz; Robyn K Pollom; Magaly Perez-Nieves; Roy Daniel Pollom; Irene Hadjiyianni
Journal:  Int J Clin Pract       Date:  2017-07-23       Impact factor: 2.503

Review 9.  Optimizing Glycemic Control Through Titration of Insulin Glargine 100 U/mL: A Review of Current and Future Approaches with a Focus on Asian Populations.

Authors:  Chaicharn Deerochanawong; Shailendra Bajpai; I Made Pande Dwipayana; Zanariah Hussein; Maria Aileen Mabunay; Reynaldo Rosales; Shih-Tzer Tsai; Man Wo Tsang
Journal:  Diabetes Ther       Date:  2017-11-01       Impact factor: 2.945

10.  Assessment of three fasting plasma glucose targets for insulin glargine-based therapy in people with type 2 diabetes mellitus in China: study protocol for a randomized controlled trial.

Authors:  Wenying Yang; Zhaojun Yang; Jing Zhao; Hai Lu; Tianhong Luo
Journal:  Trials       Date:  2016-09-26       Impact factor: 2.279

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