[Vademecum of skeletal complications of malignancy].

Bone metastasis is a frequent complication for cancer patients leading pain, fracture, spinal cord compression and hypercalcemia. A multidisciplinary approach is strongly recommended to optimize the different treatment options (i.e. radiotherapy, surgery and vertebroplasty) in the context of the underlying cancer. The effectiveness of bisphosphonates and denosumab to reduce skeletal events has widely been demonstrated. Prevention and treatment of bone complications are crucial for maintaining the independence and quality of life of patients.