Literature DB >> 23757259

Thyroxine, shape, and weight: interaction of Graves' disease and bulimia nervosa.

Martin Teufel1, Katrin Elisabeth Giel, Jule Lehr, Sandra Becker, Michaela Muthig, Stephan Zipfel, Jürgen Kuprion.   

Abstract

OBJECTIVE: A case of a 25-year-old woman with bulimia nervosa and Graves' disease is presented. Graves' disease is the cause of 50-80 % of hyperthyroidism. The disease is characterized by increases of thyroid hormone production, activation of the metabolism, and successive weight loss. Bulimia nervosa is characterized by purging behavior after binge eating episodes. METHOD AND
RESULTS: We report a patient suffering from both entities. A pronounced non-compliance to the intake of antithyroid drugs (Carbimazole) correlated with eating disorder symptoms like negative evaluation of the body and fear of weight gain. Thus, elevated hyperthyroidism due to Graves' disease served as a purging method. During 8 weeks of inpatient psychotherapy, the patient adapted to a structured eating behavior. Self-esteem was less influenced by body shape and body weight, and compliance to endocrinological recommendations improved.
CONCLUSION: Non-compliance to antithyroid drugs may be a symptom of an eating disorder. A careful and primarily non-confronting interdisciplinary diagnostic and treatment approach is required.

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Year:  2013        PMID: 23757259     DOI: 10.1007/s40519-013-0013-3

Source DB:  PubMed          Journal:  Eat Weight Disord        ISSN: 1124-4909            Impact factor:   4.652


  17 in total

Review 1.  Graves' disease.

Authors:  A P Weetman
Journal:  N Engl J Med       Date:  2000-10-26       Impact factor: 91.245

2.  Psychopathology in underweight and weight-recovered females with anorexia nervosa.

Authors:  N Schneider; H Salbach-Andrae; J V Merle; J Hein; E Pfeiffer; U Lehmkuhl; S Ehrlich
Journal:  Eat Weight Disord       Date:  2009-12       Impact factor: 4.652

3.  Cardiovascular manifestations of hyperthyroidism before and after antithyroid therapy: a matched case-control study.

Authors:  Faizel Osman; Jayne A Franklyn; Roger L Holder; Michael C Sheppard; Michael D Gammage
Journal:  J Am Coll Cardiol       Date:  2006-12-13       Impact factor: 24.094

Review 4.  Medical complications of bulimia nervosa and their treatments.

Authors:  Philip S Mehler
Journal:  Int J Eat Disord       Date:  2011-03       Impact factor: 4.861

5.  Graves' disease. Influence of age on clinical findings.

Authors:  R A Nordyke; F I Gilbert; A S Harada
Journal:  Arch Intern Med       Date:  1988-03

6.  Triiodothyronine production in Graves' hyperthyroidism.

Authors:  Kenneth A Woeber
Journal:  Thyroid       Date:  2006-07       Impact factor: 6.568

7.  [Validation of the FKB-20 as scale for the detection of body image distortions in psychosomatic patients].

Authors:  U Clement; B Löwe
Journal:  Psychother Psychosom Med Psychol       Date:  1996-07

Review 8.  Eating disorders.

Authors:  Christopher G Fairburn; Paul J Harrison
Journal:  Lancet       Date:  2003-02-01       Impact factor: 79.321

Review 9.  Psychosocial approach to endocrine disease.

Authors:  Nicoletta Sonino; Elena Tomba; Giovanni A Fava
Journal:  Adv Psychosom Med       Date:  2007

Review 10.  Pathogenesis of Graves' ophthalmopathy: the role of autoantibodies.

Authors:  Teck Kim Khoo; Rebecca S Bahn
Journal:  Thyroid       Date:  2007-10       Impact factor: 6.568

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