| Literature DB >> 23756055 |
J Gueudry1, D Boutolleau, M Gueudin, S Burrel, A Miri, B Bodaghi, M Muraine.
Abstract
Varicella-zoster virus (VZV) resistance to acyclovir (ACV) has only been reported in rare cases of immunocompromised patients. We report the first case of an immunocompetent patient with ACV-resistant VZV keratitis associated with a nucleotide deletion in the VZV thymidine kinase gene, leading to production of a truncated protein.Entities:
Keywords: Acyclovir; Cornea; Drug resistance; Herpetic keratitis; Varicella zoster virus
Mesh:
Substances:
Year: 2013 PMID: 23756055 DOI: 10.1016/j.jcv.2013.04.024
Source DB: PubMed Journal: J Clin Virol ISSN: 1386-6532 Impact factor: 3.168