Maria Browall1, Ulrika Östlund, Ingela Henoch, Yvonne Wengström. 1. School of Life Sciences, University of Skövde, Sweden; Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Division of Nursing, Stockholm, Sweden. Electronic address: maria.brovall@ki.se.
Abstract
BACKGROUND: Previous studies include too few patients over 70 years to be able to assess treatment effects on Health Related Quality Of Life (HRQOL) in the older age group. We aimed to follow HRQOL in postmenopausal women (55-80 years) with breast cancer receiving adjuvant treatment, until five years post-treatment, and compare with a general population. PATIENTS AND METHODS: The patient sample included 150 women (adjuvant CT n = 75 and RT n = 75) and two reference samples from the Swedish SF-36 norm database. RESULTS: Data from baseline showed significantly higher levels of physical functioning and general health among the patients compared to the reference sample, and significantly lower levels of bodily pain, emotional role functioning and mental health. Longitudinal analyses showed significant changes in all scales, and three different patterns (a decrease-stable, a decrease-increase, and a stable- increase pattern) were identified. CONCLUSION: Postmenopausal women seem to successfully manage the effects of adjuvant treatment on HRQOL.
BACKGROUND: Previous studies include too few patients over 70 years to be able to assess treatment effects on Health Related Quality Of Life (HRQOL) in the older age group. We aimed to follow HRQOL in postmenopausal women (55-80 years) with breast cancer receiving adjuvant treatment, until five years post-treatment, and compare with a general population. PATIENTS AND METHODS: The patient sample included 150 women (adjuvant CT n = 75 and RT n = 75) and two reference samples from the Swedish SF-36 norm database. RESULTS: Data from baseline showed significantly higher levels of physical functioning and general health among the patients compared to the reference sample, and significantly lower levels of bodily pain, emotional role functioning and mental health. Longitudinal analyses showed significant changes in all scales, and three different patterns (a decrease-stable, a decrease-increase, and a stable- increase pattern) were identified. CONCLUSION: Postmenopausal women seem to successfully manage the effects of adjuvant treatment on HRQOL.
Authors: Jonghan Yu; Woo-Seung Son; Sae Byeol Lee; Il Young Chung; Byung Ho Son; Sei Hyun Ahn; Min-Woo Jo; Jong Won Lee Journal: Health Qual Life Outcomes Date: 2018-07-20 Impact factor: 3.186
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