Literature DB >> 237518

The effect of seven vasopressors of halothane MAC in dogs.

E P Steffey, E I Eger.   

Abstract

We evaluated the effects of ephedrine, mephentermine, metaraminol, phenylephrine, methoxamine, noradrenaline and adrenaline on halothane anaesthetic requirement (MAC) in dogs. MAC increased significantly only during ephedrine infusion (50%) although significance was approached with mephentermine (21%). Phenylephrine, metaraminol, methoxamine, noradrenaline and adrenaline did not change MAC. Arterial pressure was increased 50-100% with all agents. Our results support the hypothesis that anaesthetic requirement may be related, in part, to release of brain noradrenaline.

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Year:  1975        PMID： 237518     DOI： 10.1093/bja/47.4.435

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN： 0007-0912            Impact factor:   9.166


  5 in total

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Journal:  Drug Saf       Date:  1997-02       Impact factor: 5.606

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Journal:  Br J Pharmacol       Date:  1988-06       Impact factor: 8.739

3.  The anesthetic interaction of propofol and sevoflurane on the minimum alveolar concentration preventing motor movement (MACNM) in dogs.

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Journal:  Can J Vet Res       Date:  2015-04       Impact factor: 1.310

4.  Sevoflurane-induced isoelectric EEG and burst suppression: differential and antagonistic effect of added nitrous oxide.

Authors:  B Niu; J Y Xiao; Y Fang; B Y Zhou; J Li; F Cao; Y K Tian; W Mei
Journal:  Anaesthesia       Date:  2017-03-08       Impact factor: 6.955

5.  Aminophylline and Ephedrine, but Not Flumazenil, Inhibit the Activity of the Excitatory Amino Acid Transporter 3 Expressed in Xenopus Oocytes and Reverse the Increased Activity by Propofol.

Authors:  Sohyeon Moon; Hee Jung Baik
Journal:  Biomed Res Int       Date:  2018-05-20       Impact factor: 3.411
  5 in total

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