Literature DB >> 23750681

Assessment and management of left ventricular hypertrophy in Type 2 diabetes patients with high blood pressure.

Giuseppe Derosa1, Pamela Maffioli.   

Abstract

Diabetes is associated with left ventricular hypertrophy (LVH). This article reviews the assessment and management of LVH in Type 2 diabetic patients and the available evidence on blood-pressure management in these patients in order to reduce LVH. The best treatment of LVH starts with early identification and rapid implementation of adequate treatment, especially in populations at higher risk. Angiotensin II receptor antagonists and angiotensin-converting enzyme inhibitors should be the first-line therapy, because they are proven to be the most effective in reducing LVH in Type 2 diabetic patients. In patients where angiotensin II receptor antagonists and angiotensin-converting enzyme inhibitors are contraindicated or not tolerated, calcium-channel blockers should be the second option.

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Year:  2013        PMID: 23750681     DOI: 10.1586/erc.13.36

Source DB:  PubMed          Journal:  Expert Rev Cardiovasc Ther        ISSN: 1477-9072


  2 in total

1.  Succinate causes pathological cardiomyocyte hypertrophy through GPR91 activation.

Authors:  Carla J Aguiar; João A Rocha-Franco; Pedro A Sousa; Anderson K Santos; Marina Ladeira; Cibele Rocha-Resende; Luiz O Ladeira; Rodrigo R Resende; Fernando A Botoni; Marcos Barrouin Melo; Cristiano X Lima; José M Carballido; Thiago M Cunha; Gustavo B Menezes; Silvia Guatimosim; M Fatima Leite
Journal:  Cell Commun Signal       Date:  2014-12-24       Impact factor: 5.712

2.  Barnidipine or Lercanidipine on Echocardiographic Parameters in Hypertensive, Type 2 Diabetics with Left Ventricular Hypertrophy: A Randomized Clinical Trial.

Authors:  Giuseppe Derosa; Amedeo Mugellini; Fabrizio Querci; Ivano Franzetti; Rosa Maria Pesce; Angela D'Angelo; Pamela Maffioli
Journal:  Sci Rep       Date:  2015-08-05       Impact factor: 4.379

  2 in total

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