Literature DB >> 23749834

Solid variant of papillary thyroid carcinoma in a 14-year-old girl.

Wan Faiziah Wan Abdul Rahman1, Mohd Nizam Md Hashim, Thin Thin Win, Ikmal Hisyam Bakrin.   

Abstract

Solid variant of papillary thyroid carcinoma (PTC) is a rare, poorly characterised variant and predominantly reported in children with a history of radiation exposure. This variant has a high propensity for extra-thyroidal extension and cervical lymph node metastases. A 14-year-old Malay girl who had no history of radiation exposure, presented with multiple cervical lymphadenopathy and it was clinically suspicious for tuberculosis or lymphoma. An incisional biopsy revealed a metastatic PTC. The patient underwent total thyroidectomy with bilateral lateral neck dissection and histopathology report was solid variant of PTC. Whole-body I(131) scan was performed which revealed an intense tracer uptake in the neck. She was planned for radioactive iodine ablation and now on regular follow-up for monitoring of possible tumour metastasis.

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Year:  2013        PMID: 23749834      PMCID: PMC3702920          DOI: 10.1136/bcr-2013-010001

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  7 in total

1.  Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children.

Authors:  Y E Nikiforov; J M Rowland; K E Bove; H Monforte-Munoz; J A Fagin
Journal:  Cancer Res       Date:  1997-05-01       Impact factor: 12.701

2.  Solid variant of papillary thyroid carcinoma: incidence, clinical-pathologic characteristics, molecular analysis, and biologic behavior.

Authors:  Y E Nikiforov; L A Erickson; M N Nikiforova; C M Caudill; R V Lloyd
Journal:  Am J Surg Pathol       Date:  2001-12       Impact factor: 6.394

Review 3.  Papillary thyroid carcinoma variants.

Authors:  Ricardo V Lloyd; Darya Buehler; Elham Khanafshar
Journal:  Head Neck Pathol       Date:  2011-01-08

Review 4.  Aggressive variants of papillary thyroid carcinoma.

Authors:  Carl E Silver; Randall P Owen; Juan P Rodrigo; Alessandra Rinaldo; Kenneth O Devaney; Alfio Ferlito
Journal:  Head Neck       Date:  2010-09-07       Impact factor: 3.147

5.  Thyroid lesions in children and adolescents after the Chernobyl disaster: implications for the study of radiation tumorigenesis.

Authors:  Y Nikiforov; D R Gnepp; J A Fagin
Journal:  J Clin Endocrinol Metab       Date:  1996-01       Impact factor: 5.958

Review 6.  A review of thyroid cancer with intermediate differentiation.

Authors:  Mark Sywak; Janice L Pasieka; Travis Ogilvie
Journal:  J Surg Oncol       Date:  2004-04-01       Impact factor: 3.454

7.  Solid variant of papillary carcinoma thyroid in a child with no history of radiation exposure.

Authors:  Nishikant Damle; Soundararajan Ramya; Chandrasekhar Bal; Prashant Durgapal
Journal:  Indian J Nucl Med       Date:  2011-10
  7 in total
  1 in total

1.  Solid papillary thyroid carcinoma with Hashimoto's thyroiditis: description of a further case with challenging cytological features.

Authors:  Franco Fulciniti; Jessica Barizzi; Pierpaolo Trimboli; Luca Giovanella
Journal:  BMJ Case Rep       Date:  2019-01-17
  1 in total

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