Literature DB >> 23749292

Can online benchmarking increase rates of thrombolysis? Data from the Austrian stroke unit registry.

Julia Ferrari1, Leonhard Seyfang, Wilfried Lang.   

Abstract

Despite its widespread availability and known safety and efficacy, a therapy with intravenous thrombolysis is still undergiven. We aimed to identify whether nationwide quality projects--like the stroke registry in Austria--as well as online benchmarking and predefined target values can increase rates of thrombolysis. Therefore, we assessed 6,394 out of 48,462 patients with ischemic stroke from the Austrian stroke registry (study period from March 2003 to December 2011) who had undergone thrombolysis treatment. We defined lower level and target values as quality parameters and evaluated whether or not these parameters could be achieved in the past years. We were able to show that rates of thrombolysis in Austria increased from 4.9% in 2003 to 18.3% in 2011. In a multivariate regression model, the main impact seen was the increase over the years [the OR ranges from 0.47 (95% CI 0.32-0.68) in 2003 to 2.51 (95% CI 2.20-2.87) in 2011). The predefined lower and target levels of thrombolysis were achieved at the majority of participating centers: in 2011 the lower value of 5% was achieved at all stroke units, and the target value of 15% was observed at 21 of 34 stroke units. We conclude that online benchmarking and the concept of defining target values as a tool for nationwide acute stroke care appeared to result in an increase in the rate of thrombolysis over the last few years while the variability between the stroke units has not yet been reduced.

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Year:  2013        PMID: 23749292     DOI: 10.1007/s00415-013-6964-5

Source DB:  PubMed          Journal:  J Neurol        ISSN: 0340-5354            Impact factor:   4.849


  12 in total

1.  Collaborative systematic review of the randomised trials of organised inpatient (stroke unit) care after stroke. Stroke Unit Trialists' Collaboration.

Authors: 
Journal:  BMJ       Date:  1997-04-19

2.  The main components of stroke unit care: results of a European expert survey.

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4.  Promoting thrombolysis in acute ischemic stroke.

Authors:  Maaike Dirks; Louis W Niessen; Jeroen D H van Wijngaarden; Peter J Koudstaal; Cees L Franke; Robert J van Oostenbrugge; Robbert Huijsman; Hester F Lingsma; Mirella M N Minkman; Diederik W J Dippel
Journal:  Stroke       Date:  2011-03-10       Impact factor: 7.914

5.  Tissue plasminogen activator for acute ischemic stroke.

Authors: 
Journal:  N Engl J Med       Date:  1995-12-14       Impact factor: 91.245

6.  Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke.

Authors:  Werner Hacke; Markku Kaste; Erich Bluhmki; Miroslav Brozman; Antoni Dávalos; Donata Guidetti; Vincent Larrue; Kennedy R Lees; Zakaria Medeghri; Thomas Machnig; Dietmar Schneider; Rüdiger von Kummer; Nils Wahlgren; Danilo Toni
Journal:  N Engl J Med       Date:  2008-09-25       Impact factor: 91.245

7.  European Stroke Facilities Survey: the German and Austrian perspective.

Authors:  E Bernd Ringelstein; Stefanie Meckes-Ferber; Werner Hacke; Markku Kaste; Michael Brainin; Didier Leys
Journal:  Cerebrovasc Dis       Date:  2008-11-28       Impact factor: 2.762

8.  Early clinical worsening in patients with TIA or minor stroke: the Austrian Stroke Unit Registry.

Authors:  J Ferrari; M Knoflach; S Kiechl; J Willeit; S Schnabl; L Seyfang; W Lang
Journal:  Neurology       Date:  2010-01-12       Impact factor: 9.910

9.  European Stroke Organisation recommendations to establish a stroke unit and stroke center.

Authors:  E Bernd Ringelstein; Angel Chamorro; Markku Kaste; Peter Langhorne; Didier Leys; Philippe Lyrer; Vincent Thijs; Lars Thomassen; Danilo Toni
Journal:  Stroke       Date:  2013-01-29       Impact factor: 7.914

10.  The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial.

Authors:  Peter Sandercock; Joanna M Wardlaw; Richard I Lindley; Martin Dennis; Geoff Cohen; Gordon Murray; Karen Innes; Graham Venables; Anna Czlonkowska; Adam Kobayashi; Stefano Ricci; Veronica Murray; Eivind Berge; Karsten Bruins Slot; Graeme J Hankey; Manuel Correia; Andre Peeters; Karl Matz; Phillippe Lyrer; Gord Gubitz; Stephen J Phillips; Antonio Arauz
Journal:  Lancet       Date:  2012-05-23       Impact factor: 79.321

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Journal:  Eur Stroke J       Date:  2021-04-12

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Journal:  PLoS One       Date:  2016-05-06       Impact factor: 3.240

3.  Temporal Changes in the Quality of Acute Stroke Care in Five National Audits across Europe.

Authors:  Steffi Hillmann; Silke Wiedmann; Alec Fraser; Juan Baeza; Anthony Rudd; Bo Norrving; Kjell Asplund; Maciej Niewada; Martin Dennis; Peter Hermanek; Charles D A Wolfe; Peter U Heuschmann
Journal:  Biomed Res Int       Date:  2015-12-09       Impact factor: 3.411

4.  Generalization of the right acute stroke promotive strategies in reducing delays of intravenous thrombolysis for acute ischemic stroke: A meta-analysis.

Authors:  Qiang Huang; Jing-Ze Zhang; Wen-Deng Xu; Jian Wu
Journal:  Medicine (Baltimore)       Date:  2018-06       Impact factor: 1.889

5.  Improving Outcomes Achieved by a New Stroke Program in Hungary.

Authors:  Csilla Égi; Júlia Horváth; Katalin Hahn; Bernadette Kalman; József Betlehem; Lajos Nagy
Journal:  Cerebrovasc Dis Extra       Date:  2015-10-30
  5 in total

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