Literature DB >> 23749063

A novel array format for monitoring cellular uptake using a photo-cleavable linker for peptide release.

Kenji Usui1, Takuya Kikuchi, Kin-ya Tomizaki, Takashi Kakiyama, Hisakazu Mihara.   

Abstract

We developed a novel peptide array format incorporating a photo-cleavable linker for monitoring cellular uptake. Model peptides were successfully immobilised via the photo-cleavable linker onto conventional plates and could be released spatiotemporally using UV irradiation. Incorporation of confocal microscopy allowed for detailed real-time monitoring of cellular internalisation of peptides.

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Year:  2013        PMID： 23749063     DOI： 10.1039/c3cc41632a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Effects of the properties of short peptides conjugated with cell-penetrating peptides on their internalization into cells.

Authors:  Ryo Matsumoto; Mina Okochi; Kazunori Shimizu; Kei Kanie; Ryuji Kato; Hiroyuki Honda
Journal:  Sci Rep       Date:  2015-08-10       Impact factor: 4.379

2.  Solid-phase combinatorial synthesis using microarrays of microcompartments with light-induced on-chip cell screening.

Authors:  A Rosenfeld; M Brehm; A Welle; V Trouillet; S Heissler; M Benz; P A Levkin
Journal:  Mater Today Bio       Date:  2019-08-20

3.  Mass Spectrometry-Based Solid Phase Peptide Reaction Assay for Detecting Allergenicity Using an Immobilized Peptide-Conjugating Photo-Cleavable Linker.

Authors:  Hiroshi Miyazaki; Yasutaka Samejima; Kazuya Iwata; Yuuki Minamino; Shinya Hikida; Hideto Ariumi; Hidefumi Ikeda; Yoshio Hamada; Kunihiko Yamashita; Kenji Usui
Journal:  Int J Mol Sci       Date:  2020-11-06       Impact factor: 5.923
  3 in total

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