Literature DB >> 23748556

Minimal Erythema Dose (MED) testing.

Carolyn J Heckman1, Rachel Chandler, Jacqueline D Kloss, Amy Benson, Deborah Rooney, Teja Munshi, Susan D Darlow, Clifford Perlis, Sharon L Manne, David W Oslin.   

Abstract

Ultraviolet radiation (UV) therapy is sometimes used as a treatment for various common skin conditions, including psoriasis, acne, and eczema. The dosage of UV light is prescribed according to an individual's skin sensitivity. Thus, to establish the proper dosage of UV light to administer to a patient, the patient is sometimes screened to determine a minimal erythema dose (MED), which is the amount of UV radiation that will produce minimal erythema (sunburn or redness caused by engorgement of capillaries) of an individual's skin within a few hours following exposure. This article describes how to conduct minimal erythema dose (MED) testing. There is currently no easy way to determine an appropriate UV dose for clinical or research purposes without conducting formal MED testing, requiring observation hours after testing, or informal trial and error testing with the risks of under- or over-dosing. However, some alternative methods are discussed.

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Year:  2013        PMID: 23748556      PMCID: PMC3734971          DOI: 10.3791/50175

Source DB:  PubMed          Journal:  J Vis Exp        ISSN: 1940-087X            Impact factor:   1.355


  10 in total

1.  Guidelines for dosimetry and calibration in ultraviolet radiation therapy: a report of a British Photodermatology Group workshop.

Authors:  D K Taylor; A V Anstey; A J Coleman; B L Diffey; P M Farr; J Ferguson; S Ibbotson; K Langmack; J J Lloyd; P McCann; C J Martin; H Du P Menagé; H Moseley; G Murphy; S D Pye; L E Rhodes; S Rogers
Journal:  Br J Dermatol       Date:  2002-05       Impact factor: 9.302

2.  Assessment of the usefulness of skin phototype and skin color as the parameter of cutaneous narrow band UVB sensitivity in psoriasis patients.

Authors:  Jai Il Youn; Je Young Park; Seong Jin Jo; Jong Hyun Rim; Yong Beom Choe
Journal:  Photodermatol Photoimmunol Photomed       Date:  2003-10       Impact factor: 3.135

3.  Accumulation of sunscreen in human skin after daily applications: a study of sunscreens with different ultraviolet radiation filters.

Authors:  Mette Bodekær; Ulf Akerström; Hans Christian Wulf
Journal:  Photodermatol Photoimmunol Photomed       Date:  2012-06       Impact factor: 3.135

4.  Could colorimetric method replace the individual minimal erythemal dose (MED) measurements in determining the initial dose of narrow-band UVB treatment for psoriasis patients with skin phototype III-V?

Authors:  I H Kwon; H H Kwon; S J Na; J I Youn
Journal:  J Eur Acad Dermatol Venereol       Date:  2012-02-20       Impact factor: 6.166

Review 5.  Fitzpatrick skin typing: applications in dermatology.

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Journal:  Indian J Dermatol Venereol Leprol       Date:  2009 Jan-Feb       Impact factor: 2.545

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Authors:  Ann R Webb; Richard Kift; Jacqueline L Berry; Lesley E Rhodes
Journal:  Photochem Photobiol       Date:  2011-02-14       Impact factor: 3.421

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Authors:  T B Fitzpatrick
Journal:  Arch Dermatol       Date:  1988-06

8.  Determination of the minimal phototoxic dose and colorimetry in psoralen plus ultraviolet A radiation therapy.

Authors:  Cristine Kloeckner Kraemer; Dóris Baratz Menegon; Tania Ferreira Cestari
Journal:  Photodermatol Photoimmunol Photomed       Date:  2005-10       Impact factor: 3.135

9.  Validation of a semiautomated method of minimal erythema dose testing for narrowband ultraviolet B phototherapy.

Authors:  S G H Otman; C Edwards; B Gambles; A V Anstey
Journal:  Br J Dermatol       Date:  2006-08       Impact factor: 9.302

10.  Minimal erythema dose after multiple UV exposures depends on pre-exposure skin pigmentation.

Authors:  M Henriksen; R Na; M S Agren; H C Wulf
Journal:  Photodermatol Photoimmunol Photomed       Date:  2004-08       Impact factor: 3.135

  10 in total
  13 in total

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Journal:  Int J Methods Psychiatr Res       Date:  2019-01-31       Impact factor: 4.035

3.  Safety and Efficacy of Oral Polypodium leucotomos Extract in Healthy Adult Subjects.

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Journal:  J Clin Aesthet Dermatol       Date:  2015-02

4.  Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy.

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Journal:  Oncogene       Date:  2018-05-22       Impact factor: 9.867

5.  Self-control study of combination treatment of 308 nm excimer laser and calcipotriene ointment on stable psoriasis vulgaris.

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Journal:  Int J Clin Exp Med       Date:  2014-09-15

6.  Oral Vitamin D Rapidly Attenuates Inflammation from Sunburn: An Interventional Study.

Authors:  Jeffrey F Scott; Lopa M Das; Sayeeda Ahsanuddin; Yuqi Qiu; Amy M Binko; Zachary P Traylor; Sara M Debanne; Kevin D Cooper; Rebecca Boxer; Kurt Q Lu
Journal:  J Invest Dermatol       Date:  2017-05-30       Impact factor: 8.551

7.  Transcriptome Analysis Identifies the Dysregulation of Ultraviolet Target Genes in Human Skin Cancers.

Authors:  Yao Shen; Arianna L Kim; Rong Du; Liang Liu
Journal:  PLoS One       Date:  2016-09-19       Impact factor: 3.240

Review 8.  Claimed Effects, Outcome Variables and Methods of Measurement for Health Claims Proposed Under European Community Regulation 1924/2006 in the Framework of Maintenance of Skin Function.

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Journal:  Nutrients       Date:  2017-12-22       Impact factor: 5.717

9.  A Rapid and Cost-Effective Device for Testing Minimal Erythema Dose.

Authors:  Leah Conant; Kristen M Beck; Wilson Liao
Journal:  Dermatol Ther (Heidelb)       Date:  2018-08-10

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Journal:  Nutrients       Date:  2018-03-31       Impact factor: 5.717

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