| Literature DB >> 23748212 |
Miguel Garavís1, Rebeca Bocanegra, Elías Herrero-Galán, Carlos González, Alfredo Villasante, J Ricardo Arias-Gonzalez.
Abstract
We report the first single molecule investigation of TERRA molecules. By using optical-tweezers and other biophysical techniques, we have found that long RNA constructions of up to 25 GGGUUA repeats form higher order structures comprised of single parallel G-quadruplex blocks, which unfold at lower forces than their DNA counterparts.Entities:
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Year: 2013 PMID： 23748212 DOI： 10.1039/c3cc42981d
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222