Literature DB >> 2374694

Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6.

K A Lord1, B Hoffman-Liebermann, D A Liebermann.   

Abstract

We report here the full length cDNA sequence and the deduced amino-acid sequence of MyD88, a novel myeloid differentiation primary response gene activated in M1D+ myeloid precursors, following induction of terminal differentiation and growth arrest by IL6. Detectable levels of MyD88 RNA were observed in myeloid precursor enriched murine bone-marrow, but not in several other non-myeloid murine tissues.

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Year:  1990        PMID： 2374694

Source DB:  PubMed          Journal:  Oncogene        ISSN： 0950-9232            Impact factor:   9.867


  57 in total

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4.  Deregulated c-myb disrupts interleukin-6- or leukemia inhibitory factor-induced myeloid differentiation prior to c-myc: role in leukemogenesis.

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6.  A TaqI RFLP for the human arylsulfatase A gene.

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8.  Lipopolysaccharide and IL-1β coordinate a synergy on cytokine production by upregulating MyD88 expression in human gingival fibroblasts.

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