Literature DB >> 23745757

Chemoselective benzylation of unprotected anthranilic acids with benzhydryl alcohols by water-soluble Au(III)/TPPMS in water.

Hidemasa Hikawa1, Hideharu Suzuki, Yuusaku Yokoyama, Isao Azumaya.   

Abstract

A novel and efficient method for the benzylation of unprotected anthranilic acids with benzhydryl alcohols using water-soluble Au(III)/TPPMS in water is developed. Water plays an important role in our catalytic system. This new protocol could be used for not only N-benzylation, but also chemoselective C-benzylation by the Friedel-Crafts reaction.

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Year:  2013        PMID: 23745757     DOI: 10.1021/jo401064f

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

Review 1.  Direct Substitution of Alcohols in Pure Water by Brønsted Acid Catalysis.

Authors:  Rosa Ortiz; Raquel P Herrera
Journal:  Molecules       Date:  2017-04-01       Impact factor: 4.411

  1 in total

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