Literature DB >> 23745171

Comorbidity in Atopic Dermatitis.

Eric L Simpson1.   

Abstract

The negative impact of atopic dermatitis (AD) often extends beyond the skin. Children with AD experience increased rates of infectious, mental health, and allergic diseases compared to their non-atopic peers. The mechanisms underlying these associations remain elusive. New insights from genetic and epidermal research pinpoint the skin barrier as a primary initiator of AD. Epicutaneous sensitization represents an intriguing new model which links a disrupted skin barrier to the later development of IgE-mediated diseases in patients with AD. Recent epidemiological studies have identified new comorbidities linked to AD as well, including several mental health disorders and obesity. This manuscript reviews the recent literature regarding both classic and newly described AD comorbidities.

Entities:  

Keywords:  Comorbidity; asthma; atopic dermatitis; attention-deficit-hyperactivity-disorder; autism; cancer; depression; eczema; epicutaneous sensitization; food allergy; skin barrier

Year:  2012        PMID: 23745171      PMCID: PMC3671606          DOI: 10.1007/s13671-011-0003-5

Source DB:  PubMed          Journal:  Curr Dermatol Rep        ISSN: 2162-4933


  138 in total

Review 1.  Kwashiorkor from a severe dietary restriction in an 8-month infant in suburban Detroit, Michigan: case report and review of the literature.

Authors:  Emily P Tierney; Robert J Sage; Tor Shwayder
Journal:  Int J Dermatol       Date:  2010-05       Impact factor: 2.736

Review 2.  Atopic dermatitis and cancer risk.

Authors:  H Wang; T L Diepgen
Journal:  Br J Dermatol       Date:  2006-02       Impact factor: 9.302

3.  Reductions in claudin-1 may enhance susceptibility to herpes simplex virus 1 infections in atopic dermatitis.

Authors:  Anna De Benedetto; Mark K Slifka; Nicholas M Rafaels; I-Hsin Kuo; Steve N Georas; Mark Boguniewicz; Tissa Hata; Lynda C Schneider; Jon M Hanifin; Richard L Gallo; David C Johnson; Kathleen C Barnes; Donald Y M Leung; Lisa A Beck
Journal:  J Allergy Clin Immunol       Date:  2011-04-13       Impact factor: 10.793

4.  Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice.

Authors:  J M Spergel; E Mizoguchi; J P Brewer; T R Martin; A K Bhan; R S Geha
Journal:  J Clin Invest       Date:  1998-04-15       Impact factor: 14.808

5.  Association between atopic dermatitis and obesity in adulthood.

Authors:  J I Silverberg; N B Silverberg; M Lee-Wong
Journal:  Br J Dermatol       Date:  2012-02-06       Impact factor: 9.302

6.  Is obesity a risk factor for childhood asthma?

Authors:  R von Kries; M Hermann; V P Grunert; E von Mutius
Journal:  Allergy       Date:  2001-04       Impact factor: 13.146

Review 7.  Role of bacterial pathogens in atopic dermatitis.

Authors:  Yu-Tsan Lin; Chen-Ti Wang; Bor-Luen Chiang
Journal:  Clin Rev Allergy Immunol       Date:  2007-12       Impact factor: 8.667

8.  Quality of life and disease severity are correlated in children with atopic dermatitis.

Authors:  M A Ben-Gashir; P T Seed; R J Hay
Journal:  Br J Dermatol       Date:  2004-02       Impact factor: 9.302

9.  Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum.

Authors:  Pei-Song Gao; Nicholas M Rafaels; Tracey Hand; Tanda Murray; Mark Boguniewicz; Tissa Hata; Lynda Schneider; Jon M Hanifin; Richard L Gallo; Li Gao; Terri H Beaty; Lisa A Beck; Kathleen C Barnes; Donald Y M Leung
Journal:  J Allergy Clin Immunol       Date:  2009-09       Impact factor: 10.793

10.  Development of ST-246® for Treatment of Poxvirus Infections.

Authors:  Robert Jordan; Janet M Leeds; Shanthakumar Tyavanagimatt; Dennis E Hruby
Journal:  Viruses       Date:  2010-11-03       Impact factor: 5.818

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  19 in total

1.  The Difference of Gut Microbiota and Their Correlations With Urinary Organic Acids Between Autistic Children With and Without Atopic Dermatitis.

Authors:  Ru-Ping Hong; Yue-Ying Hou; Xin-Jie Xu; Ji-Dong Lang; Yun-Feng Jin; Xiao-Feng Zeng; Xuan Zhang; Geng Tian; Xin You
Journal:  Front Cell Infect Microbiol       Date:  2022-06-21       Impact factor: 6.073

2.  Mental health comorbidity in patients with atopic dermatitis.

Authors:  Pouya Yaghmaie; Caroline W Koudelka; Eric L Simpson
Journal:  J Allergy Clin Immunol       Date:  2012-12-13       Impact factor: 10.793

Review 3.  [Dermatological diseases and their importance for psychiatry].

Authors:  P Mavrogiorgou; G Juckel
Journal:  Nervenarzt       Date:  2017-03       Impact factor: 1.214

4.  Association Between Atopic Dermatitis and Autism Spectrum Disorder: A Systematic Review and Meta-analysis.

Authors:  Tsung-Yu Tsai; Yuan-Chen Chao; Cheng-Yu Hsieh; Yu-Chen Huang
Journal:  Acta Derm Venereol       Date:  2020-05-28       Impact factor: 3.875

5.  Psychological Distress in Young Adult Males with Atopic Dermatitis: A Cross-Sectional Study.

Authors:  Si-Heon Kim; Jae Hur; Jae-Yeon Jang; Hae-Sim Park; Chang Hyung Hong; Sang Joon Son; Ki Jung Chang
Journal:  Medicine (Baltimore)       Date:  2015-06       Impact factor: 1.889

6.  Gender differences in depression and anxiety among atopic dermatitis patients.

Authors:  Shaily Mina; Masarat Jabeen; Shalini Singh; Rohit Verma
Journal:  Indian J Dermatol       Date:  2015 Mar-Apr       Impact factor: 1.494

7.  Association of Perceived Stress with Atopic Dermatitis in Adults: A Population-Based Study in Korea.

Authors:  Hyejin Park; Kisok Kim
Journal:  Int J Environ Res Public Health       Date:  2016-07-27       Impact factor: 3.390

Review 8.  The Challenge of Managing Atopic Dermatitis in the United States.

Authors:  Steven R Feldman; Linda S Cox; Lindsay C Strowd; Robert A Gerber; Steven Faulkner; Debra Sierka; Timothy W Smith; Joseph C Cappelleri; Mark E Levenberg
Journal:  Am Health Drug Benefits       Date:  2019-04

9.  The Association between Atopic Dermatitis and Depressive Symptoms in Korean Adults: The Fifth Korea National Health and Nutrition Examination Survey, 2007-2012.

Authors:  Sewon Kim; Jee-Yon Lee; Jin-Young Oh; Lan Chekal; Duk Chul Lee
Journal:  Korean J Fam Med       Date:  2015-11-20

10.  Longitudinal association between early atopic dermatitis and subsequent attention-deficit or autistic disorder: A population-based case-control study.

Authors:  Chih-Ying Lee; Mu-Hong Chen; Mei-Jy Jeng; Ju-Wei Hsu; Shih-Jen Tsai; Ya-Mei Bai; Giun-Yi Hung; Hsiu-Ju Yen; Tzeng-Ji Chen; Tung-Ping Su
Journal:  Medicine (Baltimore)       Date:  2016-09       Impact factor: 1.889

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