CONTEXT: In Iranian traditional medicine, different species of the genus Tetrataenium are used as antiseptic, spice and food additives. OBJECTIVE: The present study examined the possible antioxidant effects of hydro-alcoholic extracts of different parts of Tetrataenium lasiopetalum (Boiss.) Manden (Apiaceae). MATERIALS AND METHODS: Laminas, stems, petioles, fruits, peduncles and flowers of T. lasiopetalum were collected, dried and then extracted by ethanol and water (70:30). Antioxidant activities of extracts were examined by employing different in vitro assays, i.e., 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, metal chelating, reducing power activities and hemoglobin-induced linoleic acid system. Also, total phenolic and flavonoid contents of the extracts were evaluated. RESULTS: Hydro-alcoholic extract of T. lasiopetalum flower showed the highest activity in scavenging of DPPH (IC50 = 170 ± 7 μg/mL). In metal chelating assay, lamina extract possesses a better iron ion chelating activity than other extracts (230 ± 10 μg/mL). Lamina hydro-alcoholic extract demonstrated better activity in reducing the power and hemoglobin-induced linoleic acid system than other parts of T. lasiopetalum. DISCUSSION AND CONCLUSION: These results showed the antioxidant activity of different parts of T. lasiopetalum based on its usage in traditional medicine.
CONTEXT: In Iranian traditional medicine, different species of the genus Tetrataenium are used as antiseptic, spice and food additives. OBJECTIVE: The present study examined the possible antioxidant effects of hydro-alcoholic extracts of different parts of Tetrataenium lasiopetalum (Boiss.) Manden (Apiaceae). MATERIALS AND METHODS: Laminas, stems, petioles, fruits, peduncles and flowers of T. lasiopetalum were collected, dried and then extracted by ethanol and water (70:30). Antioxidant activities of extracts were examined by employing different in vitro assays, i.e., 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, metal chelating, reducing power activities and hemoglobin-induced linoleic acid system. Also, total phenolic and flavonoid contents of the extracts were evaluated. RESULTS: Hydro-alcoholic extract of T. lasiopetalum flower showed the highest activity in scavenging of DPPH (IC50 = 170 ± 7 μg/mL). In metal chelating assay, lamina extract possesses a better iron ion chelating activity than other extracts (230 ± 10 μg/mL). Lamina hydro-alcoholic extract demonstrated better activity in reducing the power and hemoglobin-induced linoleic acid system than other parts of T. lasiopetalum. DISCUSSION AND CONCLUSION: These results showed the antioxidant activity of different parts of T. lasiopetalum based on its usage in traditional medicine.
Authors: Zobaer Al Mahmud; Sitesh C Bachar; Choudhury Mahmood Hasan; Talha Bin Emran; Nazmul Qais; Mir Muhammad Nasir Uddin Journal: BMC Res Notes Date: 2017-07-06