Literature DB >> 23741974

DNMT3A mutations at R882 hotspot are only found in major clones of acute myeloid leukemia.

Kathrin E Bisling1, John N Brewin, Andrew P McGovern, Gillian A Horne, Tom Rider, Helen J Stewart, Bernard H Ramsahoye, Timothy J Chevassut.   

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Year:  2013        PMID： 23741974     DOI： 10.3109/10428194.2013.811580

Source DB:  PubMed          Journal:  Leuk Lymphoma        ISSN： 1026-8022


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  3 in total

1.  BRD4 associates with p53 in DNMT3A-mutated leukemia cells and is implicated in apoptosis by the bromodomain inhibitor JQ1.

Authors:  Helen Jayne Susan Stewart; Gillian Abigail Horne; Sarah Bastow; Timothy James Telfer Chevassut
Journal:  Cancer Med       Date:  2013-10-31       Impact factor: 4.452

2.  Driver mutations of cancer epigenomes.

Authors:  David M Roy; Logan A Walsh; Timothy A Chan
Journal:  Protein Cell       Date:  2014-03-14       Impact factor: 14.870

3.  Rapid detection of DNMT3A R882 mutations in hematologic malignancies using a novel bead-based suspension assay with BNA(NC) probes.

Authors:  Velizar Shivarov; Milena Ivanova; Elissaveta Naumova
Journal:  PLoS One       Date:  2014-06-10       Impact factor: 3.240
  3 in total

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