Literature DB >> 23741670

Melanoacanthoma: Uncommon presentation of an uncommon condition.

Resham J Vasani1, Swapna S Khatu.   

Abstract

Melanoacanthoma is very rare variant of seborrheic keratosis presenting as a deeply pigmented benign proliferation of melanocytes and keratinocytes usually presenting over the head, neck and trunk of elderly people. A sixty-two-years-old male was presented with a solitary slow growing asymptomatic hyperpigmented verrucous outgrowth with cerebriform surface measuring 15 cm by 8 cm present over the left inguinal region extending on to the scrotum since past 8 years. There was no associated lymphadenopathy. The histopathology revealed hyperkeratosis, papillomatosis, acanthosis with presence of melanocytes at all levels of epidermis with abundant melanin giving the diagnosis of melanoacanthoma. The patient further underwent surgical excision of the lesion. The case is being reported for its rarity, unusual location, massive size and clinical resemblance to a verrucous carcinoma.

Entities:  

Keywords:  Melanoacanthoma; pigmented seborrheic keratosis; verrucous carcinoma

Year:  2013        PMID: 23741670      PMCID: PMC3673377          DOI: 10.4103/2229-5178.110638

Source DB:  PubMed          Journal:  Indian Dermatol Online J        ISSN: 2229-5178


  4 in total

1.  Benign mixed tumor of melanocytes and malpighian cells. Melanoacanthoma: Its relationship to Bloch's benign non-nevoid melanoepithelioma.

Authors:  Y MISHIMA; H PINKUS
Journal:  Arch Dermatol       Date:  1960-04

2.  Melanoacanthoma. Ultrastructural and immunological studies.

Authors:  O L Schlappner; G Rowden; T M Philips; Z Rahim
Journal:  J Cutan Pathol       Date:  1978-06       Impact factor: 1.587

3.  Oral melanoacanthoma: a report of 10 cases, review of the literature, and immunohistochemical analysis for HMB-45 reactivity.

Authors:  Maria L Fornatora; Renee F Reich; Sol Haber; Frederick Solomon; Paul D Freedman
Journal:  Am J Dermatopathol       Date:  2003-02       Impact factor: 1.533

4.  Giant melanoacanthoma mimicking malignant melanoma.

Authors:  Vikas Shankar; Jayoti Nandi; Kisalay Ghosh; Sanjay Ghosh
Journal:  Indian J Dermatol       Date:  2011-01       Impact factor: 1.494

  4 in total
  1 in total

1.  Melanoacanthoma Masquerading as Melanoma: Case Reports and Literature Review.

Authors:  Nikolas Gutierrez; Christof P Erickson; Antoanella Calame; Brooke R Sateesh; Philip R Cohen
Journal:  Cureus       Date:  2019-06-25
  1 in total

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