Literature DB >> 23739288

Granulocyte colony-stimulating factor receptor T595I (T618I) mutation confers ligand independence and enhanced signaling.

H M Mehta1, T Glaubach, A Long, H Lu, B Przychodzen, H Makishima, M A McDevitt, N C P Cross, J Maciejewski, S J Corey.   

Abstract

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Year:  2013        PMID： 23739288     DOI： 10.1038/leu.2013.164

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  16 in total

1.  Alternatively spliced, truncated GCSF receptor promotes leukemogenic properties and sensitivity to JAK inhibition.

Authors:  H M Mehta; M Futami; T Glaubach; D W Lee; J R Andolina; Q Yang; Z Whichard; M Quinn; H F Lu; W M Kao; B Przychodzen; C A Sarkar; A Minella; J P Maciejewski; S J Corey
Journal:  Leukemia       Date:  2013-10-30       Impact factor: 11.528

2.  Severe congenital neutropenia and chronic neutrophilic leukemia: an intriguing molecular connection unveiled by oncogenic mutations in CSF3R.

Authors:  Ivo P Touw; Renée Beekman
Journal:  Haematologica       Date:  2013-10       Impact factor: 9.941

3.  Ligand independence of the T618I mutation in the colony-stimulating factor 3 receptor (CSF3R) protein results from loss of O-linked glycosylation and increased receptor dimerization.

Authors:  Julia E Maxson; Samuel B Luty; Jason D MacManiman; Melissa L Abel; Brian J Druker; Jeffrey W Tyner
Journal:  J Biol Chem       Date:  2014-01-08       Impact factor: 5.157

4.  The Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I.

Authors:  Julia E Maxson; Samuel B Luty; Jason D MacManiman; Jason C Paik; Jason Gotlib; Peter Greenberg; Swaleh Bahamadi; Samantha L Savage; Melissa L Abel; Christopher A Eide; Marc M Loriaux; Emily A Stevens; Jeffrey W Tyner
Journal:  Clin Cancer Res       Date:  2015-10-16       Impact factor: 12.531

5.  Gain-of-function mutations in granulocyte colony-stimulating factor receptor (CSF3R) reveal distinct mechanisms of CSF3R activation.

Authors:  Haijiao Zhang; Cody Coblentz; Kevin Watanabe-Smith; Sophie Means; Jasmine Means; Julia E Maxson; Jeffrey W Tyner
Journal:  J Biol Chem       Date:  2018-03-23       Impact factor: 5.157

Review 6.  Cytokine receptor splice variants in hematologic diseases.

Authors:  Borwyn Wang; Hrishikesh Mehta
Journal:  Cytokine       Date:  2019-12-06       Impact factor: 3.861

Review 7.  Granulocyte colony-stimulating factor receptor signaling in severe congenital neutropenia, chronic neutrophilic leukemia, and related malignancies.

Authors:  Pankaj Dwivedi; Kenneth D Greis
Journal:  Exp Hematol       Date:  2016-10-24       Impact factor: 3.084

Review 8.  G-CSF and GM-CSF in Neutropenia.

Authors:  Hrishikesh M Mehta; Michael Malandra; Seth J Corey
Journal:  J Immunol       Date:  2015-08-15       Impact factor: 5.422

Review 9.  Granulocyte colony-stimulating factor receptor mutations in myeloid malignancy.

Authors:  Clifford Liongue; Alister Curtis Ward
Journal:  Front Oncol       Date:  2014-05-01       Impact factor: 6.244

10.  Characterization of the leukemogenic potential of distal cytoplasmic CSF3R truncation and missense mutations.

Authors:  H Zhang; A Reister Schultz; S Luty; A Rofelty; Y Su; S Means; D Bottomly; B Wilmot; S K McWeeney; J W Tyner
Journal:  Leukemia       Date:  2017-04-25       Impact factor: 11.528
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