| Literature DB >> 23738614 |
Wei Zhao1, Darla M Fink, Carolyn A Labutta, Alexander T Radosevich.
Abstract
The preparation of densely functionalized unsymmetrical 1,4-dicarbonyl structural motifs by a phosphorus(III)-mediated reductive condensation of α-keto esters and enolizable carbon pronucleophiles is described. The reaction, which is initiated by Kukhtin-Ramirez addition of commercially available tris(dimethylamino)phosphine to the α-keto ester substrate, proceeds rapidly under mild conditions.Entities:
Mesh：
Substances：
Year: 2013 PMID： 23738614 DOI： 10.1021/ol401276b
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005