Literature DB >> 23737589

Thyroid associated orbitopathy.

Rajesh Verma1, Mani Gupta, Vinod Kumar Mehta.   

Abstract

Thyroid-associated orbitopathy (TAO) is a self-limiting auto-immune condition usually associated with Grave's disease. It is characterised by ocular pain, eyelid swelling, chemosis, proptosis and keratopathy. As the mechanism for ophthamoplegia and optic neuropathy is the orbital swelling leading to mechanical restriction of ocular muscles and compression of optic nerve, one expects proptosis rather than ptosis in TAO. We describe a case of a young adult woman who presented with acute onset restriction of movement along with partial ptosis and severe diminution of vision in left eye. The MRI of orbit revealed significant swelling of recti along with signal alteration consistent with TAO. The radio-isotope thyroid scan revealed thyroiditis, and thyroid peroxidase (TPO) antibody was significantly high; hence, the diagnosis of Hashimoto thyroiditis was considered. A course of intravenous methylprednisolone followed by oral steroid was administered, which produced marked improvement in vision and extraocular movement.

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Year:  2013        PMID: 23737589      PMCID: PMC3703025          DOI: 10.1136/bcr-2013-009920

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  13 in total

Review 1.  Imaging in thyroid-associated orbitopathy.

Authors:  G J Kahaly
Journal:  Eur J Endocrinol       Date:  2001-08       Impact factor: 6.664

Review 2.  Thyroiditis.

Authors:  Elizabeth N Pearce; Alan P Farwell; Lewis E Braverman
Journal:  N Engl J Med       Date:  2003-06-26       Impact factor: 91.245

Review 3.  Orbital apex syndrome.

Authors:  Steven Yeh; Rod Foroozan
Journal:  Curr Opin Ophthalmol       Date:  2004-12       Impact factor: 3.761

Review 4.  Study on the treatment of traumatic orbital apex syndrome by nasal endoscopic surgery.

Authors:  Youzhong Li; Weijing Wu; Zian Xiao; Anquan Peng
Journal:  Eur Arch Otorhinolaryngol       Date:  2010-10-27       Impact factor: 2.503

Review 5.  Thyroid associated ophthalmopathy - a review.

Authors:  Ps Mallika; Ak Tan; S Aziz; Sar Syed Alwi; Ms Chong; R Vanitha; G Intan
Journal:  Malays Fam Physician       Date:  2009-04-30

6.  A rare case of orbital apex syndrome with herpes zoster ophthalmicus in a human immunodeficiency virus-positive patient.

Authors:  Rohit Saxena; Swati Phuljhele; Lalit Aalok; Ankur Sinha; Vimla Menon; Pradeep Sharma; Anant Mohan
Journal:  Indian J Ophthalmol       Date:  2010 Nov-Dec       Impact factor: 1.848

Review 7.  Thyroid associated orbitopathy.

Authors:  Rajat Maheshwari; Ezekiel Weis
Journal:  Indian J Ophthalmol       Date:  2012 Mar-Apr       Impact factor: 1.848

8.  Orbital apex syndrome associated with herpes zoster ophthalmicus.

Authors:  Takuji Kurimoto; Masahiro Tonari; Norihiko Ishizaki; Mitsuhiro Monta; Saori Hirata; Hidehiro Oku; Jun Sugasawa; Tsunehiko Ikeda
Journal:  Clin Ophthalmol       Date:  2011-11-09

9.  Primary Adenoid Cystic Carcinoma Presenting as an Orbital Apex Tumor.

Authors:  Ramachandran Venkitaraman; Jayaprakash Madhavan; Krishnankuttynair Ramachandran; Elizabeth Abraham; Balakrishnan Rajan
Journal:  Neuroophthalmology       Date:  2008

Review 10.  Imaging studies for diagnosing Graves' orbitopathy and dysthyroid optic neuropathy.

Authors:  Allan C Pieroni Gonçalves; Eloísa M M S Gebrim; Mário L R Monteiro
Journal:  Clinics (Sao Paulo)       Date:  2012-11       Impact factor: 2.365

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  2 in total

1.  Hashimoto's thyroiditis associated with acute painful unilateral ophthalmoplegia.

Authors:  Byungseok Kim; Taewon Kim
Journal:  Neurol Sci       Date:  2019-08-05       Impact factor: 3.307

2.  Not All Orbitopathy Is Graves': Discussion of Cases and Review of Literature.

Authors:  Neeraja Boddu; Maliha Jumani; Vibhor Wadhwa; Gitanjali Bajaj; Fred Faas
Journal:  Front Endocrinol (Lausanne)       Date:  2017-07-31       Impact factor: 5.555

  2 in total

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