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Literature DB >> 23737435

Transporting and shielding photosensitisers by using water-soluble organometallic cages: a new strategy in drug delivery and photodynamic therapy.

Abstract

Skin photosensitivity remains one of the main limitations in photodynamic therapy. In this Concept article a strategy to overcome this limitation is described, in which the photosensitizer is hidden inside the hydrophobic cavity of a water-soluble organometallic cage. The metallacage not only protects the photosensitizer from light, it also facilitates its delivery to cancer cells.

Entities: Chemical Disease

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Year: 2013 PMID： 23737435 DOI： 10.1002/chem.201301348

Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236

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Cited

11 in total

1. Design and Applications of Water-Soluble Coordination Cages.

Authors: Edmundo G Percástegui; Tanya K Ronson; Jonathan R Nitschke
Journal: Chem Rev Date: 2020-11-25 Impact factor: 60.622

Review 2. The development of anticancer ruthenium(ii) complexes: from single molecule compounds to nanomaterials.

Authors: Leli Zeng; Pranav Gupta; Yanglu Chen; Enju Wang; Liangnian Ji; Hui Chao; Zhe-Sheng Chen
Journal: Chem Soc Rev Date: 2017-10-02 Impact factor: 54.564

3. BODIPY based Metal-Organic Macrocycles and Frameworks: Recent Therapeutic Developments.

Authors: Gajendra Gupta; Yan Sun; Abhishek Das; Peter J Stang; Chang Yeon Lee
Journal: Coord Chem Rev Date: 2021-11-22 Impact factor: 22.315

Review 4. Supramolecular coordination complexes as diagnostic and therapeutic agents.

Authors: Guocan Yu; Meijuan Jiang; Feihe Huang; Xiaoyuan Chen
Journal: Curr Opin Chem Biol Date: 2020-10-23 Impact factor: 8.822

5. Dicopper(II) and dizinc(II) complexes with nonsymmetric dinucleating ligands based on indolo[3,2-c]quinolines: synthesis, structure, cytotoxicity, and intracellular distribution.

Authors: Michael F Primik; Simone Göschl; Samuel M Meier; Nadine Eberherr; Michael A Jakupec; Éva A Enyedy; Ghenadie Novitchi; Vladimir B Arion
Journal: Inorg Chem Date: 2013-08-16 Impact factor: 5.165

6. pH-dependent binding of guests in the cavity of a polyhedral coordination cage: reversible uptake and release of drug molecules.

Authors: William Cullen; Simon Turega; Christopher A Hunter; Michael D Ward
Journal: Chem Sci Date: 2014-07-31 Impact factor: 9.825

Transporting and shielding photosensitisers by using water-soluble organometallic cages: a new strategy in drug delivery and photodynamic therapy.

1. Design and Applications of Water-Soluble Coordination Cages.

Review 2. The development of anticancer ruthenium(ii) complexes: from single molecule compounds to nanomaterials.

3. BODIPY based Metal-Organic Macrocycles and Frameworks: Recent Therapeutic Developments.

Review 4. Supramolecular coordination complexes as diagnostic and therapeutic agents.

5. Dicopper(II) and dizinc(II) complexes with nonsymmetric dinucleating ligands based on indolo[3,2-c]quinolines: synthesis, structure, cytotoxicity, and intracellular distribution.

6. pH-dependent binding of guests in the cavity of a polyhedral coordination cage: reversible uptake and release of drug molecules.

7. A Self-Assembled Electro-Active M8L4 Cage Based on Tetrathiafulvalene Ligands.

8. Self-Assembly of a [1 + 1] Ionic Hexagonal Macrocycle and Its Antiproliferative Activity.

9. A Quantitative Study of the Effects of Guest Flexibility on Binding Inside a Coordination Cage Host.

10. Investigation of the biological and anti-cancer properties of ellagic acid-encapsulated nano-sized metalla-cages.