Literature DB >> 23735849

Survival of acute hypernatremia due to massive soy sauce ingestion.

David J Carlberg1, Heather A Borek, Scott A Syverud, Christopher P Holstege.   

Abstract

BACKGROUND: Intentional massive sodium chloride ingestions are rare occurrences and are often fatal.
OBJECTIVES: There are a variety of treatment recommendations for hypernatremia, ranging from dialysis to varying rates of correction. We report a case of acute severe hypernatremia corrected with rapid free-water infusions that, to our knowledge, has not been previously reported. CASE REPORT: A 19-year-old man presented to the Emergency Department in a comatose state with seizure-like activity 2 hours after ingesting a quart of soy sauce. He was administered 6 L of free water over 30 min and survived neurologically intact without clinical sequelae. Corrected for hyperglycemia, the patient's peak serum sodium was 196 mmol/L, which, to our knowledge, is the highest documented level in an adult patient to survive an acute sodium ingestion without neurologic deficits.
CONCLUSION: Emergency physicians should consider rapidly lowering serum sodium with hypotonic intravenous fluids as a potential management strategy for acute severe hypernatremia secondary to massive salt ingestion.
Copyright © 2013 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  acute hypernatremia; hypotonic fluids; resuscitation; sodium chloride

Mesh:

Substances:

Year:  2013        PMID: 23735849     DOI: 10.1016/j.jemermed.2012.11.109

Source DB:  PubMed          Journal:  J Emerg Med        ISSN: 0736-4679            Impact factor:   1.484


  6 in total

1.  Fatal acute hypernatremia resulting from a massive intake of seasoning soy sauce.

Authors:  Ayaka Sakamoto; Tetsuya Hoshino; Keishun Boku; Daigo Hiraya; Yoshiaki Inoue
Journal:  Acute Med Surg       Date:  2020-08-20

Review 2.  Hypertonicity: Clinical entities, manifestations and treatment.

Authors:  Helbert Rondon-Berrios; Christos Argyropoulos; Todd S Ing; Dominic S Raj; Deepak Malhotra; Emmanuel I Agaba; Mark Rohrscheib; Zeid J Khitan; Glen H Murata; Joseph I Shapiro; Antonios H Tzamaloukas
Journal:  World J Nephrol       Date:  2017-01-06

Review 3.  A Systematic Review of Fatalities Related to Acute Ingestion of Salt. A Need for Warning Labels?

Authors:  Norm R C Campbell; Emma J Train
Journal:  Nutrients       Date:  2017-06-23       Impact factor: 5.717

4.  Treatment of acute hypernatremia caused by sodium overload in adults: A systematic review.

Authors:  Takahiro Goshima; Teruhiko Terasawa; Mitsunaga Iwata; Asako Matsushima; Tomonori Hattori; Hiroshi Sasano
Journal:  Medicine (Baltimore)       Date:  2022-02-25       Impact factor: 1.817

5.  Histological Identification and Quantification of Eosinophils and Ascites in Leghorn Chickens Treated with High Oral Concentrations of NaCl-Pilot Study.

Authors:  Victor M Petrone-Garcia; Inkar Alejandro Castellanos-Huerta; Saeed El-Ashram; Marco A Juárez-Estrada; Benjamin Fuente-Martínez; Danielle B Graham; Guillermo Tellez-Isaias
Journal:  Toxics       Date:  2022-07-09

6.  Neuroprotective and antioxidant activities of bamboo salt soy sauce against H2O2-induced oxidative stress in rat cortical neurons.

Authors:  Jong Hee Jeong; Min-Young Noh; Jae-Hyeok Choi; Haiwon Lee; Seung Hyun Kim
Journal:  Exp Ther Med       Date:  2016-02-09       Impact factor: 2.447

  6 in total

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